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Rabbit Anti-CEACAM16/Gold Conjugated antibody (bs-7998R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-7998R-Gold
英文名稱1 Rabbit Anti-CEACAM16/Gold Conjugated antibody
中文名稱 膠體金標記的癌胚抗原相關(guān)細胞粘附分子16抗體
別    名 Carcinoembryonic antigen like 2; Carcinoembryonic antigen like 2 protein; Carcinoembryonic antigen related cell adhesion molecule 16; CEAL2; CEA16_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細胞生物  免疫學  細胞粘附分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from hu CEACAM16/CEAL2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
The protein encoded by this gene is a secreted glycoprotein that in mouse interacts with tectorial membrane proteins in the inner ear. The encoded adhesion protein is found in cochlear outer hair cells and appears to be important for proper hearing over an extended frequency range. Defects in this gene likely are a cause of non-syndromic autosomal dominant hearing loss. [provided by RefSeq, May 2012].

Function:
May play a role in maintaining the integrity of the tectorial membrane.

Subunit:
Monomer. Homodimer. Tetramer. Interacts with TECTA.

Subcellular Location:
Secreted. Note=Localizes to the tip of cochlear outer hair cells and to the tectorial membrane (By similarity).

DISEASE:
Defects in CEACAM16 are the cause of deafness autosomal dominant type 4B (DFNA4B) [MIM:614614]. A form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information.

Similarity:
Belongs to the immunoglobulin superfamily. CEA family.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Database links:
UniProtKB/Swiss-Prot: Q2WEN9.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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