吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
精品人妻大屁股白浆无码,妓女嫖客叫床粗话对白
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-Lin-28B/PE-Cy3 Conjugated antibody (bs-6446R-PE-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-6446R-PE-Cy3
英文名稱1 Rabbit Anti-Lin-28B/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標記的RNA結(jié)合蛋白LIN28B抗體
別    名 Lin28B; CSDD 2; CSDD2; FLJ16517; Lin 28 homolog B (C. elegans); Lin 28.2; Lin-28B; LIN28B; LN28B_HUMAN; Protein lin-28 homolog B.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Rat,  (predicted: Mouse, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Lin-28B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation. Mediates MYC-mediated let-7 repression. Isoform 1, when overexpressed, stimulates growth of the breast adenocarcinoma cell line MCF-7. Isoform 2 has no effect on cell growth.

Function:
Acts as a suppressor of microRNA (miRNA) biogenesis by specifically binding the precursor let-7 (pre-let-7), a miRNA precursor. Acts by binding pre-let-7 and recruiting ZCCHC11/TUT4 uridylyltransferase, leading to the terminal uridylation of pre-let-7. Uridylated pre-let-7 miRNAs fail to be processed by Dicer and undergo degradation. Specifically recognizes the 5'-GGAG-3' motif in the terminal loop of pre-let-7. Also recognizes and binds non pre-let-7 pre-miRNAs that contain the 5'-GGAG-3' motif in the terminal loop, leading to their terminal uridylation and subsequent degradation. Mediates MYC-mediated let-7 repression. Isoform 1, when overexpressed, stimulates growth of the breast adenocarcinoma cell line MCF-7. Isoform 2 has no effect on cell growth.

Subunit:
Interacts with ZCCHC11/TUT4.

Subcellular Location:
Cytoplasm. Nucleus. Predominantly cytoplasmic at G1 phase, accumulates in the nucleus in S and G2 phases. The frequency of nuclear localization in S and in G2 phases is 60% and 30%, respectively.

Tissue Specificity:
High expression in testis, fetal liver, placenta and in hepatocellular carcinoma (HCC). Isoform 1 is only detected in moderately and poorly differentiated HCC tissues and placenta (at protein level). Isoform 2 is detected in fetal liver, non-tumor liver tissues, as well as well-differentiated tumor tissues (at protein level).

Similarity:
Belongs to the lin-28 family.
Contains 2 CCHC-type zinc fingers.
Contains 1 CSD (cold-shock) domain.

Database links:

Entrez Gene: 389421 Human

Entrez Gene: 380669 Mouse

Omim: 611044 Human

SwissProt: Q6ZN17 Human

SwissProt: Q45KJ6 Mouse

Unigene: 23616 Human

Unigene: 440328 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
精品白嫩BBWBBWBBW| 久久精品国产一区二区电影| 男生被男人CAO屁股的后果| 99久久精品免费看国产| 人妻无码久久一区二区三区免费| 99国产精品久久久久久久成人热| 人人人妻人人澡人人爽欧美一区| 久久精品| 久久久久亚洲AV无码专区网站| 老熟妇仑乱一区二区视頻| 欧洲人妻丰满AV无码久久不卡| 国产裸体舞一区二区三区| 欧美成A人片在线观看久| 一本狠狠色丁香婷婷综合久久| 欧洲亚洲国产精华液| 公交车被两根粗大同进同出| 人人妻人人澡人人爽欧美一区| 女女女女BBBBBB毛片在线| 日本特黄特色aaa大片免费| 99久久无码一区人妻A片| 小SAO货揉揉你的奶真大视频| WWW国产精品内射老熟女 | 少妇夹得好紧太爽了A片| 小荡货奶真大水多好紧视频| 丰满熟妇大肉唇张开| 一本久久综合亚洲鲁鲁五月天| 嗯快点别停舒服好爽受不了了| 粉嫩XB粉嫩XB粉嫩XB| 亚洲AV无码国产精品色| 国产精品久久久久久岛| 国产特级毛片A片WWW| 亚洲AV无码久久寂寞少妇| 国产99久一区二区三区A片| 适合晚上一个人看B站软件| 亚洲精品无码久久久| 亚洲色婷婷一区二区三区| 亚洲AV无码国产精品久久不卡| 久久精品99国产精品日本 | 国产产无码乱码精品久久鸭| 亚洲欧美激情精品一区二区| 欧洲AV无码放荡人妇网站|