| 產(chǎn)品編號 | bs-0075R-BF488 |
| 英文名稱1 | Rabbit Anti-Nociceptin/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的孤菲肽/痛敏肽抗體 |
| 別 名 | PNOC; N/OFQ; N23K; N23K/N27K; Nociceptin, included; Npnc1; OFQ; OFQ/N; Orphanin FQ; PPNOC; prepronociceptin; Propronociceptin; PNOC_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 心血管 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat, (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 20kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Nociceptin (130-146aa) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Nociceptin (PNOC) is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. Expressed predominantly in the spinal cord and brain, being more abundant in the hypothalamus and striatum. Also found in small amounts in ovary. Belongs to the opioid neuropeptide precursor family. Function: Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development (By similarity). Subcellular Location: Secreted. Tissue Specificity: Predominantly in the brain and spinal cord. Similarity: Belongs to the opioid neuropeptide precursor family. Database links: Entrez Gene: 5368 Human Entrez Gene: 18155 Mouse Omim: 601459 Human SwissProt: Q13519 Human SwissProt: Q64387 Mouse Unigene: 88218 Human Unigene: 16347 Mouse Unigene: 486163 Mouse Unigene: 87935 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 孤菲肽（Nociceptin又稱為Orphanin FQ; PPNOC; ORL1）是新發(fā)現(xiàn)的一種神經(jīng)肽，由17個氨基酸組成，又稱痛敏肽。消化道腫瘤病人的血漿中OFQ含量明顯高于對照組，尤以結(jié)腸癌、胃癌最為明顯。 |
