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Rabbit Anti-Nociceptin/BF647 Conjugated antibody (bs-0075R-BF647)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-0075R-BF647
英文名稱(chēng)1 Rabbit Anti-Nociceptin/BF647 Conjugated antibody
中文名稱(chēng) BF647標(biāo)記的孤菲肽/痛敏肽抗體
別    名 PNOC; N/OFQ; N23K; N23K/N27K; Nociceptin, included; Npnc1; OFQ; OFQ/N; Orphanin FQ; PPNOC; prepronociceptin; Propronociceptin; PNOC_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  心血管  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nociceptin (130-146aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Nociceptin (PNOC) is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. Expressed predominantly in the spinal cord and brain, being more abundant in the hypothalamus and striatum. Also found in small amounts in ovary. Belongs to the opioid neuropeptide precursor family.


Function:
Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development (By similarity).

Subcellular Location:
Secreted.

Tissue Specificity:
Predominantly in the brain and spinal cord.

Similarity:
Belongs to the opioid neuropeptide precursor family.

Database links:

Entrez Gene: 5368 Human

Entrez Gene: 18155 Mouse

Entrez Gene: 25516 Rat

Omim: 601459 Human

SwissProt: Q13519 Human

SwissProt: Q64387 Mouse

SwissProt: Q62923 Rat

Unigene: 88218 Human

Unigene: 16347 Mouse

Unigene: 486163 Mouse

Unigene: 87935 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

孤菲肽(Nociceptin又稱(chēng)為Orphanin FQ; PPNOC; ORL1)是新發(fā)現(xiàn)的一種神經(jīng)肽,由17個(gè)氨基酸組成,又稱(chēng)痛敏肽。消化道腫瘤病人的血漿中OFQ含量明顯高于對(duì)照組,尤以結(jié)腸癌、胃癌最為明顯。
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