吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
少妇高潮抽搐无码AV久久,99国产精品无码
Rabbit Anti-NFATC4/AP Conjugated antibody (bs-6461R-AP)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-6461R-AP
英文名稱1 Rabbit Anti-NFATC4/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的T細(xì)胞激活核轉(zhuǎn)錄因子4抗體
別    名 NF-ATc4; NFATC4 cytoplasmic 4; NF ATc4; NF-AT3; NF-ATc4; NFAC4_HUMAN; NFAT3; NFATc4; Nuclear factor of activated T cells cytoplasmic 4; Nuclear factor of activated T cells cytoplasmic calcineurin dependent 4; Nuclear factor of activated T-cells; nuclear factor of activated T-cells cytoplasmic 4; Nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 4; T cell transcription factor NFAT3; T-cell transcription factor NFAT3.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  淋巴細(xì)胞  t-淋巴細(xì)胞  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 95kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NF-ATc4 (475-525aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The product of this gene is a member of the nuclearfactors of activated T cells DNA-binding transcription complex.This complex consists of at least two components: a preexistingcytosolic component that translocates to the nucleus upon T cellreceptor (TCR) stimulation and an inducible nuclear component.Other members of this family of nuclear factors of activated Tcells also participate in the formation of this complex. Theproduct of this gene plays a role in the inducible expression ofcytokine genes in T cells, especially in the induction of the IL-2and IL-4. Alternatively spliced transcript variants encodingdifferent isoforms have been noted for this gene.

Function:
Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.

Subunit:
Member of the multicomponent NFATC transcription complex that consists of at least two components, a pre-existing cytoplasmic component NFATC2 and an inducible nuclear component NFATC1. Other members such as NFATC4, NFATC3 or members of the activating protein-1 family, MAF, GATA4 and Cbp/p300 can also bind the complex. NFATC proteins bind to DNA as monomers. Interacts with CREBBP, GATA4, IRAK1, MAPK8, MAPK9 and RPS6KA3.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustained and transient calcium signals. The subcellular localization of NFATC plays a key role in the regulation of gene transcription.

Tissue Specificity:
Highly expressed in placenta, lung, kidney, testis and ovary. Weakly expressed in spleen and thymus. Not expressed in peripheral blood lymphocytes. Detected in hippocampus.

Post-translational modifications:
Phosphorylated by NFATC-kinases; dephosphorylated bycalcineurin. Phosphorylated on Ser-168 and Ser-170 by MTOR, IRAK1,MAPK7 and MAPK14, on Ser-213 and Ser-217 by MAPK8 and MAPK9, and onSer-289 and Ser-344 by RPS6KA3. Phosphorylated by GSK3B.
Ubiquitinated, leading to its degradation by the proteasomeand reduced transcriptional activity. Ubiquitination and reductionin transcriptional activity can be further facilitated throughGSK3B-dependent phosphorylation. Polyubiquitin linkage is mainlythrough 'Lys-48'.

Similarity:
Contains 1 IPT/TIG domain.
Contains 1 RHD (Rel-like) domain.

Database links:

Entrez Gene: 4776 Human

Entrez Gene: 73181 Mouse

Entrez Gene: 305897 Rat

Omim: 602699 Human

SwissProt: Q14934 Human

SwissProt: Q8K120 Mouse

Unigene: 77810 Human

Unigene: 27908 Mouse

Unigene: 23727 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
国产精品亚洲一区二区无码| 国产99在线 | 欧美| 欧美69久成人做爰视频| 大白肥妇BBVBBW高潮| 久久精品国产一区二区电影| 国产日产欧产美| 国产精品人妻一区夜夜爱| 日本55丰满熟妇厨房伦| 国产免费无码一区二区视频| 久久久久久久女国产乱让韩| 久久久久亚洲AV无码专区首JN| 欧美与黑人午夜性猛交久久久| 中文字幕乱码人妻无码久久| 亚洲性爱视频| 午夜精品久久久久久毛片| 影音先锋资源站| 无码AⅤ精品一区二区三区| 精品国产成人亚洲午夜福利| 亚洲AV永久无码精品一百度影院 | 亚洲AV无码一区二区三区DV| 国产AV国片偷人妻麻豆| 国产精品内射后入合集| 精品一区二区三区在线视频| 亚洲熟妇色XXXXX欧美老妇Y| 偷拍真实夫妇作爱视频| 亚洲AV日韩AV永久无码色欲| 亚洲精品无码高潮喷水A片软| 丁香色欲久久久久久综合网| 中文字幕AV久久一区二区| 亚洲娇小与黑人巨大交| 熟睡人妻被讨厌的公侵犯| 中文字幕乱码无码人妻系列蜜桃| 疯狂的肥岳交换130部小短片| 日韩亚洲av人人夜夜澡人人爽| 无码GOGO大胆啪啪艺术| 亚洲大码熟女在线观看| 久久人人爽天天玩人人妻精品| 国产肉体XXXX裸体784大胆| 神马影院| 亚洲综合AV一区二区三区| CAOPOREN免费精品视频|