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Rabbit Anti-RNF19B/BF594 Conjugated antibody (bs-9246R-BF594)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-9246R-BF594
英文名稱1 Rabbit Anti-RNF19B/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的環(huán)指蛋白19B抗體
別    名 E3 ubiquitin-protein ligase RNF19B; IBR domain containing 3; IBR domain-containing protein 3; IBRDC3; Natural killer lytic-associated molecule; NKLAM; RING finger protein 19B; RN19B_HUMAN; rnf19b.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  t-淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 78kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RNF19B
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.

Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.

Subunit:
Interacts with UBE2L3, UBE2L6 and UCKL1.

Subcellular Location:
Cytoplasmic granule membrane.

Tissue Specificity:
Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells. Present in natural killer cells

Similarity:
Belongs to the RBR family. RNF19 subfamily.
Contains 1 IBR-type zinc finger.
Contains 2 RING-type zinc fingers.

Database links:

Entrez Gene: 127544 Human

Omim: 610872 Human

SwissProt: Q6ZMZ0 Human

Unigene: 591504 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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