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Rabbit Anti-FAD24/NOC3L/Gold Conjugated antibody (bs-9713R-Gold)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書(shū): 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-9713R-Gold
英文名稱(chēng)1 Rabbit Anti-FAD24/NOC3L/Gold Conjugated antibody
中文名稱(chēng) 膠體金標(biāo)記的脂肪細(xì)胞分化因子24抗體
別    名 C10orf117; FAD24; AD24; Factor for adipocyte differentiation 24; NOC3 like protein; NOC3 protein homolog; NOC3-like protein; noc3l; NOC3L_HUMAN; Nucleolar complex associated 3 homolog (S. cerevisiae); Nucleolar complex associated protein 3 like protein; Nucleolar complex protein 3 homolog; Nucleolar complex-associated protein 3-like protein.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul(10nm  15nm  35nm
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞周期蛋白  細(xì)胞分化  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 93kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NOC3L/FAD24
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
GADD 153, a growth arrest and DNA damage-inducible gene, encodes a C/EBP-related nuclear protein. This protein has also been designated C/EBP-homologous protein (CHOP-10 or C/EBP zeta). GADD 153 expression is induced by a variety of cellular stresses, inducing nutrient deprivation and metabolic perturbations. GADD 153 functions to block cells in G1 to S phase during cell cycle progression and acts by dimerizing with other C/EBP proteins to direct GADD 153 dimers away from “classical” C/EBP binding sites, recognizing instead unique “nonclassical” sites. Thus, GADD 153 acts as a negative modulator of C/EBP-like proteins in certain terminally differentiated cells. GADD 153 belongs to the CBF/MAK21 family, which also includes NOC2L, NOC3L and NOC4L. NOC3L, also designated factor for adipocyte differentiation 24 or Fad24, promotes adipogenesis by controlling DNA replication during the early stages of mitotic clonal expansion (MCE).

Function:
May be required for adipogenesis.

Subcellular Location:
Nucleus

Tissue Specificity:
Expressed in colon, heart, kidney, liver, lung, placenta, skeletal muscle, small intestine, spleen and thymus.

Similarity:
Belongs to the CBF/MAK21 family.

Database links:

Entrez Gene: 64318 Human

Omim: 610769 Human

SwissProt: Q8WTT2 Human

Unigene: 74899 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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