吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
99久久国产精品免费热7788,国产精品人成视频免费播放,国产又色又爽又高潮免费
Rabbit Anti-Phospho-Caspase-9 (Ser196)/Gold Conjugated antibody (bs-5241R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-5241R-Gold
英文名稱1 Rabbit Anti-Phospho-Caspase-9 (Ser196)/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的磷酸化半胱氨酸蛋白酶9抗體
別    名 APAF 3; APAF3; Apoptosis related cysteine peptidase; Apoptotic protease activating factor 3; Apoptotic protease Mch 6; CASP 9; CASP9; Caspase 9 Dominant Negative; Caspase 9 precursor; Caspase 9c; Caspase9; EC 3.4.22.; ICE LAP6; ICE like apoptotic protease 6; MCH6 antibody RNCASP9; CASP9_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  免疫學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Rat, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 35kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human CASP9 around the phosphorylation site of Ser196
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6), apoptotic protease Mch6, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain. This caspase is active as a heterotetramer and has been reported to have two isoforms. ProCaspase 9 has been reported to be approximately 47 kD. This caspase is present in the cytosol and, upon activation, translocates to the mitochondria. Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6. Caspase 9 is inhibited by the dominant negative isoform, BclXL, cIAP1, cIAP2, XIAP, and Livin. This caspase becomes activated when recruited to Apaf1/cytochrome c complex, and following cleavage by Apaf1, granzyme B, Caspase 3, possibly Caspase 8 and Caspase 10 into large p37 and small p10 subunits. Caspase 9 intereacts with BIRC7 and has been shown to cleave PARP and vimentin.

Function:
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Subunit:
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 35 kDa (p35) and a 10 kDa (p10) subunit. Caspase-9 and APAF1 bind to each other via their respective NH2-terminal CED-3 homologous domains in the presence of cytochrome C and ATP. Interacts with the inhibitors BIRC2, BIRC4, BIRC5 and BIRC7. Interacts (inactive form) with EFHD2. Interacts with HAX1.

Tissue Specificity:
Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.

Post-translational modifications:
Cleavages at Asp-315 by granzyme B and at Asp-330 by caspase-3 generate the two active subunits. Caspase-8 and -10 can also be involved in these processing events.
Phosphorylated at Thr-125 by MAPK1/ERK2. Phosphorylation at Thr-125 is sufficient to block caspase-9 processing and subsequent caspase-3 activation.

Similarity:
Belongs to the peptidase C14A family.
Contains 1 CARD domain.

Database links:
UniProtKB/Swiss-Prot: P55211.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Caspase-9半胱氨酸蛋白酶家族成員之一,又稱ICE-Lap6(ICE Like apoptotease 6)參與細(xì)胞凋亡過程和細(xì)胞因子的加工過程,在許多胚胎和成人組織中都有分布。此抗體主要用于腫瘤凋亡的研究。
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
夜里十大禁用直播APP| 女人与公拘交酡全过程| 精品亚洲一区二区三区四区五区| 老熟女草BX×| 亚洲精品午夜国产VA久久成人| 荫蒂每天被男人添| 欧美啪啪| 少妇荡乳情欲办公室456视频| 亚洲色成人网站WWW永久四虎| 被黑人猛躁10次高潮视频| 成人免费毛片aaaaaa片| 中文字幕人妻丝袜乱一区三区| 国产美女自慰在线观看| 熟妇高潮精品一区二区三区| 张柏芝做爰全过程视频| 国产精品99久久久久久宅男| 国产精品成人国产乱| 和尚吮她的花蒂和奶水视频| 国产av人人夜夜澡人人爽麻豆| 好吊视频一区二区三区| 欧美《熟妇的荡欲》未删减版| 久久精品国产亚洲AV麻豆蜜芽| 成年免费a级毛片免费看无码| 伊人久久精品一区二区三区| 无遮挡国产高潮视频免费观看| 国产XXXXX精品AV青椒| 久久精品国产亚洲AV麻豆| 机长脔到她哭H粗话H动漫| AV下页| 国产在线国偷精品免费看| 驯服人妻HD中字日本| 久久偷看各类WC女厕嘘嘘偷窃| 无码人妻一区二区三区在线| 欧美XXXXX高潮喷水麻豆| 国产69久久精品成人看| 欧美一区二区三区激情| 亚洲一码和欧洲二码的尺码区别 | 影音先锋人妻啪啪AV资源网站| 成品人短视频APP推荐下载| 日韩欧美亚洲国产精品字幕久久久| 纯爱无遮挡H肉动漫在线播放|