吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
少妇被多人C夜夜爽爽AV,娇妻借朋友高H繁交H,国产一区二区三区不卡AV
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-CD133 antigen/Cy3 Conjugated antibody (bs-0209R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0209R-Cy3
英文名稱1 Rabbit Anti-CD133 antigen/Cy3 Conjugated antibody
中文名稱 Cy3標記的造血干細胞抗原CD133抗體
別    名 AC133; Antigen AC133; Hematopoietic stem cell antigen; hProminin; PROM1; Prominin I; Prominin like protein 1 precursor; Prominin mouse like 1; prominin1; PROML1; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4; PROM1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  免疫學  干細胞  細胞表面分子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Fruit Fly, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 95kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD133 antigen
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Function:
Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

Subunit:
Interacts with CDHR1 and with actin filaments.

Subcellular Location:
Cell projection, cilium, photoreceptor outer segment. Isoform 1: Apical cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Note=Found in extracellular membrane particles in various body fluids such as cerebrospinal fluid, saliva, seminal fluid and urine.

Tissue Specificity:
Isoform 1 is selectively expressed on CD34 hematopoietic stem and progenitor cells in adult and fetal bone marrow, fetal liver, cord blood and adult peripheral blood. Isoform 1 is not detected on other blood cells. Isoform 1 is also expressed in a number of non-lymphoid tissues including retina, pancreas, placenta, kidney, liver, lung, brain and heart. Found in saliva within small membrane particles. Isoform 2 is predominantly expressed in fetal liver, skeletal muscle, kidney, and heart as well as adult pancreas, kidney, liver, lung, and placenta. Isoform 2 is highly expressed in fetal liver, low in bone marrow, and barely detectable in peripheral blood. Isoform 2 is expressed on hematopoietic stem cells and in epidermal basal cells (at protein level). Expressed in adult retina by rod and cone photoreceptor cells (at protein level).

Post-translational modifications:
Isoform 1 and isoform 2 are glycosylated.

DISEASE:
Defects in PROM1 are the cause of retinitis pigmentosa type 41 (RP41) [MIM:612095]; also known as retinal degeneration autosomal recessive prominin-related. RP is a retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
Defects in PROM1 are the cause of cone-rod dystrophy type 12 (CORD12) [MIM:612657]. CORD12 is an inherited retinal dystrophy characterized by retinal pigment deposits visible on fundus examination, predominantly in the macular region, and initial loss of cone photoreceptors followed by rod degeneration. This leads to decreased visual acuity and sensitivity in the central visual field, followed by loss of peripheral vision. Severe loss of vision occurs earlier than in retinitis pigmentosa.
Defects in PROM1 are the cause of Stargardt disease type 4 (STGD4) [MIM:603786]. Stargardt disease is the most common hereditary macular degeneration. It is characterized by decreased central vision, atrophy of the macula and underlying retinal pigment epithelium, and frequent presence of prominent flecks in the posterior pole of the retina.
Defects in PROM1 are the cause of retinal macular dystrophy type 2 (MCDR2) [MIM:608051]. MCDR2 is a bull's-eye macular dystrophy characterized by bilateral annular atrophy of retinal pigment epithelium at the macula.

Similarity:
Belongs to the prominin family.

Database links:

Entrez Gene: 8842 Human

Entrez Gene: 19126 Mouse

SwissProt: O43490 Human

SwissProt: O54990 Mouse





Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

干細胞標志物
一般認為,VEGFR2(血管內(nèi)皮生長因子受體2)是HSCs(造血干細胞)的特異性的表面標志。近來經(jīng)研究發(fā)現(xiàn)CD133分子是HSCs(造血干細胞)特異性標志。CD133即AC133,是一個新發(fā)現(xiàn)的HSCs(造血干細胞)表面標志,在HSCs(造血干細胞)分化成熟過程中,CD133的含量迅速降低。EPCs(血管內(nèi)皮前體細胞)區(qū)別于成熟內(nèi)皮細胞的主要標志是CD133。
經(jīng)研究發(fā)現(xiàn)內(nèi)皮細胞不能結(jié)合CD 133的抗體。證實分化成熟的內(nèi)皮細胞不具有CD133。這些說明CD133可以作為EPCs(血管內(nèi)皮前體細胞)區(qū)別于成熟內(nèi)皮細胞的一個表面標志.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
亚洲日韩一区精品射精| 性色AV浪潮AV色欲AV一区| JAPANESE内射×××| 手机电影在线观看| 女人18毛片A级毛片| 无码视频一区二区三区| 国产AV人人夜夜澡人人爽麻豆| 久久精品人妻一区二区三区| 欧洲AV无码放荡人妇网站| 欧洲熟妇色XXXXX欧美老妇伦| 中文字幕日韩一区二区三区不卡 | 精品人妻一区二区三区浪潮在线| 国产精品永久免费视频| 久久香蕉国产线熟妇人妻| 亚州少妇无套内射激情视频| 中字幕视频在线永久在线观看免费 | 97精品国产手机| 国产精品婷婷久久爽一下| 国产特级毛片A片WWW | 久久无码人妻丰满熟妇区毛片| 欧美最猛黑人XXXXX猛交| 曰曰摸日日碰夜夜爽歪歪| 医院人妻闷声隔着帘子被中出| 中国丰满人妻VIDEOSHD| 国产真人无遮挡作爱免费视频| 图片区小说区另类春色首页| 国产免费av片在线无码免费看| 国产成人亚洲精品| 欧美老熟妇乱大交XXXXX| 中文在线А√在线| 欧美性受xxxx黑人xyx性爽 | 国产精品久久久久久人妻精品| 欧美熟妇另类久久久久久不卡| 久久久久99精品成人片试看 | 日韩精品极品视频在线观看免费| 国产精品污WWW一区二区三区| 日产精品久久久久久久| 性少妇freesexvideos高清| 欧美ZC0O人与善交另类A片 | 久久亚洲精品中文字幕| S货C货大声点叫|