吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
久久精品国产亚洲AV成人,亚洲成AV人片在线观看无码
Rabbit Anti-epithelial Sodium Channel gamma/BF488 Conjugated antibody (bs-4263R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4263R-BF488
英文名稱1 Rabbit Anti-epithelial Sodium Channel gamma/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的上皮鈉離子通道蛋白γ/γENaC抗體
別    名 Amiloride sensitive epithelial sodium channel gamma subunit; Amiloride sensitive sodium channel subunit gamma; ENaC gamma subunit; ENaCg; ENaCgamma; Epithelial Na(+) channel subunit gamma; Epithelial Na+ channel subunit gamma; Gamma ENaC; Gamma NaCH; Nonvoltage gated sodium channel 1 subunit gamma; PHA 1; PHA1; SCNEG; SCNN 1G; SCNN1G; Sodium channel nonvoltage gated 1 gamma; SCNNG_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  通道蛋白  細(xì)胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human epithelial Sodium Channel gamma
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region. There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein. ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure. ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel. Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel’s syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).

Function:
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Subunit:
Probable heterotrimer containing one alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2.

Subcellular Location:
Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells.

Post-translational modifications:
Phosphorylated on serine and threonine residues.
Ubiquitinated; this targets individual subunits for endocytosis and proteasome-mediated degradation.

DISEASE:
Defects in SCNN1G are a cause of Liddle syndrome (LIDDS) [MIM:177200]. It is an autosomal dominant disorder characterized by pseudoaldosteronism and hypertension associated with hypokalemic alkalosis. The disease is caused by constitutive activation of the renal epithelial sodium channel.
Defects in SCNN1G are the cause of bronchiectasis with or without elevated sweat chloride type 3 (BESC3) [MIM:613071]. A debilitating respiratory disease characterized by chronic, abnormal dilatation of the bronchi and other cystic fibrosis-like symptoms in the absence of known causes of bronchiectasis (cystic fibrosis, autoimmune diseases, ciliary dyskinesia, common variable immunodeficiency, foreign body obstruction). Clinical features include sub-normal lung function, sinopulmonary infections, chronic productive cough, excessive sputum production, and elevated sweat chloride in some cases.

Similarity:
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.

Database links:

Entrez Gene: 6340 Human

Entrez Gene: 20278 Mouse

Entrez Gene: 24768 Rat

Omim: 600761 Human

SwissProt: P51170 Human

SwissProt: Q9WU39 Mouse

SwissProt: Q28738 Rabbit

SwissProt: P37091 Rat

Unigene: 371727 Human

Unigene: 35247 Mouse

Unigene: 10360 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
乌克兰少妇XXXX做受野外| 性色AV一区二区三区| 精品夜夜澡人妻无码AV蜜桃| 国产精产国品一二三产区区别| 久久99精品久久久久婷婷 | 强行无套内谢大学生初次| 精品人妻无码一区二区三区| 拍摄av现场失控高潮数次| 欧美又色又爽又黄的A片18禁| 永久黄网站色视频免费直播 | 少妇伦子伦精品无码| 妽妽用身体满足了我| 天天夜碰日日摸日日澡性色AV| 免费精品人在线二线三线区别| 青青草原综合久久大伊人精品 | T66Y最新地址一地址二地址三| 亚洲精品午夜国产VA久久成人| 欧美人与物VIDEOS另类| 亚洲AV无码一区二区二三区入口| 日韩精品无码中文字幕一区二区| 亚洲第一AV网站| 亚洲熟妇AV一区二区三区| 又粗又黄又猛又爽大片免费| 欧美虐SM另类残忍视频| 国产精品无码免费专区午夜| 天堂√最新版中文在线| AV毛片| 我的SM经历1一25章| 两女女百合互慰AV赤裸无遮挡| 久久无码人妻精品一区二区三区| 精品一区二区久久久久久久网站| 欧美性生交XXXXX久久久| 97精品国产一区二区三区| 日本动漫在线| 日本熟妇色XXXXX日本免费看| 欧美熟妇另类久久久久久不卡| 亚洲日韩一区精品射精| 亚洲色精品三区二区一区| 人妻夜夜爽天天爽| 国产精品成人无码免费| 粗大的内捧猛烈进出在线视频|