吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
99无码熟妇丰满人妻啪啪,精品久久久久久无码人妻中文,小鸡庄园每日答案汇总
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-epithelial Sodium Channel gamma/BF647 Conjugated antibody (bs-4263R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-4263R-BF647
英文名稱1 Rabbit Anti-epithelial Sodium Channel gamma/BF647 Conjugated antibody
中文名稱 BF647標記的上皮鈉離子通道蛋白γ/γENaC抗體
別    名 Amiloride sensitive epithelial sodium channel gamma subunit; Amiloride sensitive sodium channel subunit gamma; ENaC gamma subunit; ENaCg; ENaCgamma; Epithelial Na(+) channel subunit gamma; Epithelial Na+ channel subunit gamma; Gamma ENaC; Gamma NaCH; Nonvoltage gated sodium channel 1 subunit gamma; PHA 1; PHA1; SCNEG; SCNN 1G; SCNN1G; Sodium channel nonvoltage gated 1 gamma; SCNNG_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學  神經(jīng)生物學  信號轉(zhuǎn)導  通道蛋白  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 71kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human epithelial Sodium Channel gamma
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Epithelial sodium channels are amiloride-sensitive members of the Degenerin/epithelial sodium channel (Deg/ENaC) superfamily of ion channels. Members of this superfamily of ion channels share organizational similarity in that they all possess two short intracellular amino and carboxyl termini, two short membrane spanning segments, and a large extracellular loop with a conserved cysteine-rich region. There are three homologous isoforms of the ENaC (alpha, beta, and gamma) protein. ENaC in the kidney, lung, and colon plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium reabsorption in the distal nephron of the kidney, thus regulating blood pressure. ENaC is thought to be regulated, in part, through association with the cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion channel. Gain-of-function mutations in beta- or gamma-ENaC can cause severe arterial hypertension (Liddel’s syndrome) and loss-of-function mutations in alpha- or beta-ENaC causes pseudohypoaldosteronism (PHA-1).

Function:
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Subunit:
Probable heterotrimer containing one alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2.

Subcellular Location:
Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells.

Post-translational modifications:
Phosphorylated on serine and threonine residues.
Ubiquitinated; this targets individual subunits for endocytosis and proteasome-mediated degradation.

DISEASE:
Defects in SCNN1G are a cause of Liddle syndrome (LIDDS) [MIM:177200]. It is an autosomal dominant disorder characterized by pseudoaldosteronism and hypertension associated with hypokalemic alkalosis. The disease is caused by constitutive activation of the renal epithelial sodium channel.
Defects in SCNN1G are the cause of bronchiectasis with or without elevated sweat chloride type 3 (BESC3) [MIM:613071]. A debilitating respiratory disease characterized by chronic, abnormal dilatation of the bronchi and other cystic fibrosis-like symptoms in the absence of known causes of bronchiectasis (cystic fibrosis, autoimmune diseases, ciliary dyskinesia, common variable immunodeficiency, foreign body obstruction). Clinical features include sub-normal lung function, sinopulmonary infections, chronic productive cough, excessive sputum production, and elevated sweat chloride in some cases.

Similarity:
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1G subfamily.

Database links:

Entrez Gene: 6340 Human

Entrez Gene: 20278 Mouse

Entrez Gene: 24768 Rat

Omim: 600761 Human

SwissProt: P51170 Human

SwissProt: Q9WU39 Mouse

SwissProt: Q28738 Rabbit

SwissProt: P37091 Rat

Unigene: 371727 Human

Unigene: 35247 Mouse

Unigene: 10360 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
99精品国产在热久久无码| 一本色道久久综合亚洲精| 日韩亚洲av人人夜夜澡人人爽| 亚洲AV中文无码乱人伦在线视色| 国产又爽又黄无码无遮挡在线观看 | 黑人猛挺进小莹的体内视频| 一个人看的WWW片免费高清中文| 农村熟女XXXXHD做受| 久久久久亚洲精品中文字幕| 精品少妇爆乳无码AV无码专区| 亚洲码欧美码一区二区三区| 少妇伦子伦精品无码| 精品亚洲麻豆1区2区3区| 嫩草伊人久久精品少妇AV网站| 亚洲精品午夜国产VA久久成人| 性xxxxfreexxxxxvideo| 精品一区二区三区在线观看| 久久影院午夜理论片无码| 欧美性猛交XXXX乱大交 | 国产女人AAA级久久久级| 欧美激情在线播放| 免费观看少妇全黄A片| 国产精品一卡二卡三卡| 影音先锋资源站| 欧美日韩免费做爰大片人| 亚洲AV片不卡无码久久| 亚洲AV无码专区在线观看下载| 女厕偷窥一区二区三区| 中文字幕丰满乱孑伦无码专区| АⅤ资源天堂资源库在线| CHINESE性内射高清国产| 久久久久久AV无码免费看大片| 夜夜躁狠狠躁2021| 久久久久亚洲AV无码专区喷水| 精品国产乱码久久久久久1区2区| A级A片少妇高潮喷水片 | 国产精品日本一区二区不卡视频| 自拍偷在线精品自拍偷无码专区| 亚洲国产成人片在线观看无码 | 国产精品第一页| 亚洲日韩AV无码|