| 產品編號 | bs-5712R-Gold |
| 英文名稱1 | Rabbit Anti-FGFR1OP/Gold Conjugated antibody |
| 中文名稱 | 膠體金標記的成纖維細胞生長因子受體1原癌基因伴侶蛋白抗體 |
| 別 名 | FGFR1OP; Fibroblast growth factor receptor 1 oncogene partner; FOP; FR1OP_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領域 | 腫瘤 細胞生物 免疫學 神經生物學 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human, Mouse, Rat, Horse, ) |
| 產品應用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 43kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FGFR1OP |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產品介紹 |
background: FGFR1 Oncogene Partner is required for anchoring microtubules to the centrosomes. Ubiquitous; highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas. A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). There are three named isoforms. Function: Required for anchoring microtubules to the centrosomes. Subunit: Homodimer. Part of a ternary complex that contains CEP350, FGFR1OP and MAPRE1. Interacts directly with CEP350 and MAPRE1. Subcellular Location: Cytoplasm, cytoskeleton, centrosome. Note=Associated with gamma-tubulin. Tissue Specificity: Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas. DISEASE: Note=A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). Translocation t(6;8)(q27;p11) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion proteins FGFR1OP-FGFR1 or FGFR1-FGFR1OP may exhibit constitutive kinase activity and be responsible for the transforming activity. Similarity: Belongs to the FGFR1OP family. Contains 1 LisH domain. Database links: Entrez Gene: 11116 Human Entrez Gene: 75296 Mouse Omim: 605392 Human SwissProt: Human SwissProt: O95684 Human SwissProt: Q66JX5 Mouse Unigene: 487175 Human Unigene: 227250 Mouse Unigene: 166829 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. FGFR1OP蛋白最初是在引起干細胞骨髓增生病的癌蛋白中作為FGFR1的融合伴侶被發(fā)現的，目前研究認為，FGFR1OP蛋白在很多組織細胞中都有不同的存在，尤其是以腦, 心，肝，肌肉，腎，小腸，結腸，腎上腺，前列腺，睪丸和胰腺中高表達。 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
