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Rabbit Anti-TAG1/FITC Conjugated antibody (bs-5845R-FITC)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-5845R-FITC
英文名稱1 Rabbit Anti-TAG1/FITC Conjugated antibody
中文名稱 FITC標(biāo)記的瞬時(shí)表達(dá)軸索糖蛋白1抗體
別    名 Axonal glycoprotein TAG 1; Axonal glycoprotein TAG-1; Axonal glycoprotein TAG1; Axonin 1; Axonin-1; Axonin1; AXT; CNTN 2; Cntn2; CNTN2_HUMAN; contactin 2 (axonal); Contactin 2; Contactin-2; Contactin2; DKFZp781D102; MGC157722; TAG 1; TAG 564; TAG564; TAX 1; TAX; TAX-1; TAX1; Transient axonal glycoprotein 1; Transiently expressed axonal glycoprotein.   
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  神經(jīng)生物學(xué)  生長(zhǎng)因子和激素  細(xì)胞粘附分子  細(xì)胞外基質(zhì)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 107kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TAG1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Contactin 2 is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunogobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.

Function:
May play a role in the initial growth and guidance of axons. May be involved in cell adhesion.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.

Similarity:
Belongs to the immunoglobulin superfamily. Contactin family.
Contains 4 fibronectin type-III domains.
Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

Database links:

Entrez Gene: 6900 Human

Entrez Gene: 21367 Mouse

Entrez Gene: 25356 Rat

Omim: 190197 Human

SwissProt: Q02246 Human

SwissProt: Q61330 Mouse

SwissProt: P22063 Rat

Unigene: 519220 Human

Unigene: 260861 Mouse

Unigene: 89910 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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