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Rabbit Anti-CAMTA1/Gold Conjugated antibody (bs-5995R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術支持:techsupport@xucheq.com
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-5995R-Gold
英文名稱1 Rabbit Anti-CAMTA1/Gold Conjugated antibody
中文名稱 膠體金標記的鈣調蛋白結合轉錄激活因子1抗體
別    名 Calmodulin-binding transcription activator 1; Calmodulin binding transcription activator 1; CMTA1; KIAA0833; CMTA1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  細胞生物  免疫學  染色質和核信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 183kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CAMTA1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
CAMTA1 is a transcription activator which is a putatuove tumor suppressor. It is thought to interact with calmodulin. Defects in CAMTA1 are detected in patients with oligodendroglioma and astrocytoma.

Function:
Transcriptional activator. May act as a tumor suppressor.

Subunit:
May interact with calmodulin (Potential).

Subcellular Location:
Nucleus (Probable). Cytoplasm.

Tissue Specificity:
Normally expressed in non-neoplastic adult central nervous system tissues: detected in whole brain, cerebellum, brain cortex, occipital lobe, frontal lobe, temporal lobe, putamen. Expression levels are low in oligodendroglial tumors, and are reduced by half in oligodendroglioma and astrocytoma cases with 1p loss of heterozygosity. Detected in neuroblastic-type cultured neuroblastoma cells. Expressed in heart and kidney.

Similarity:
Belongs to the CAMTA family.
Contains 3 ANK repeats.
Contains 1 CG-1 DNA-binding domain.
Contains 1 IPT/TIG domain.
Contains 3 IQ domains.

Database links:

Entrez Gene: 23261 Human

Entrez Gene: 100072 Mouse

Omim: 611501 Human

SwissProt: Q9Y6Y1 Human

SwissProt: A2A898 Mouse

Unigene: 397705 Human

Unigene: 671020 Human

Unigene: 318846 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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