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Rabbit Anti-CHURC1/BF488 Conjugated antibody (bs-11820R-BF488)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11820R-BF488
英文名稱1 Rabbit Anti-CHURC1/BF488 Conjugated antibody
中文名稱 BF488標記的神經(jīng)誘導胚胎發(fā)育相關蛋白Churchill抗體
別    名 CHURC-1; C14orf52; CHCH; CHURC 1; Churchill domain containing 1; FLJ33064; My015; Protein Churchill; CHUR_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  發(fā)育生物學  神經(jīng)生物學  信號轉導  生長因子和激素  轉錄調節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CHURC1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
CHURC1 is a 112 amino acid protein that plays a critical role in neural induction during embryogenesis. The fibroblast growth family of proteins (FGFs) has been identified as necessary factors in mesoderm formation and neural induction. CHURC1, a putative zinc finger protein, is a transcriptional activator that mediates FGF signaling. Furthermore, CHURC1 is thought to play a role in the regulation of cell movement. Although CHURC1 does not bind to DNA, it functions as a transcriptional regulator and a protein-interaction factor. Two isoforms of CHURC1 exist as a result of alternative splicing events.

Function:
CHURC 1 belongs to the Churchill family. It is a transcriptional activator that mediates FGF signaling during neural development. It plays a role in the regulation of cell movement, but does not bind DNA by itself. There are two named isoforms.

Similarity:
Belongs to the Churchill family.

Database links:
UniProtKB/Swiss-Prot: Q8WUH1.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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