吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
机长脔到她哭H粗话H动漫 ,欧美老熟妇又粗又大
Rabbit Anti-KALRN/BF647 Conjugated antibody (bs-11861R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-11861R-BF647
英文名稱1 Rabbit Anti-KALRN/BF647 Conjugated antibody
中文名稱 BF647標(biāo)記的舞蹈癥相關(guān)蛋白KALRN抗體
別    名 Duo; FLJ16443; HAPIP; Huntingtin associated protein interacting protein (duo) ; Huntingtin-associated protein-interacting protein; Kalirin (isoform 2); Kalirin; KALRN ; KALRN_HUMAN ; Protein Duo; RhoGEF kinase; Serine/threonine kinase with Dbl and pleckstrin homology domains ; Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain; TRAD.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  生長因子和激素  激酶和磷酸酶  細(xì)胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 340kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KALRN/Duo
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
HAP1 (huntingtin-associated protein 1) binds to huntingtin. Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region. HAP1 shows neuronal localization and moves with huntingtin in nerve fibers. HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem. Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons. Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.

Function:
Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.

Subunit:
Interacts with the C-terminal of peptidylglycine alpha-amidating monooxygenase (PAM) and with the huntingtin-associated protein 1 (HAP1) (By similarity). Interacts with FASLG.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with the cytoskeleton.

Tissue Specificity:
Isoform 2 is brain specific. Highly expressed in cerebral cortex, putamen, amygdala, hippocampus and caudate nucleus. Weakly expressed in brain stem and cerebellum. Isoform 4 is expressed in skeletal muscle.

Post-translational modifications:
Autophosphorylated.

DISEASE:
Genetic variation in KALRN is associated with susceptibility to coronary heart disease type 5 (CHDS5) [MIM:608901]. CHD is the leading cause of death and disability worldwide. CHD is multifactorial disease with a strong genetic component. Classic epidemiologic studies have revealed many risk factors for CHD, including age, sex, hypertension, dyslipidemia, diabetes mellitus, smoking, and physical inactivity.

Similarity:
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Contains 1 CRAL-TRIO domain.
Contains 2 DH (DBL-homology) domains.
Contains 1 fibronectin type-III domain.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 2 PH domains.
Contains 1 protein kinase domain.
Contains 2 SH3 domains. Contains 5 spectrin repeats.

Database links:

Entrez Gene: 8997 Human

Entrez Gene: 545156 Mouse

Entrez Gene: 84009 Rat

Omim: 604605 Human

SwissProt: O60229 Human

SwissProt: A2CG49 Mouse

SwissProt: P97924 Rat

Unigene: 8004 Human

Unigene: 353103 Mouse

Unigene: 450612 Mouse

Unigene: 82274 Mouse

Unigene: 87882 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
久久久精品欧美一区二区免费| 强行无套内谢大学生初次| 97久久精品人人做人人爽| 国产精品无码一区二区三区| 国产精品久久久久一区二区三区| WC凹凸撒尿间谍女厕HD| 粉嫩名器少妇名器| 成人午夜福利视频| 日韩乱码人妻无码中文字幕久久| 免费男人下部进女人下部视频| CHINESE猛男自慰GV网站| 亚洲欧美自偷自拍另类小说 | CHINA中国妞TUBESEX| 国产精品无码电影在线观看| 免费人成在线观看网站体验站| 人妻中文字幕乱人伦在线| 69精品丰满人妻无码视频A片 | 97在线视频人妻无码| 色窝窝无码一区二区三区成人网站| 最近免费中文字幕中文高清6| 国内大量揄拍人妻精品視頻| 亚洲AV日韩精品久久久久久久| 公和我在野外做好爽爱爱小说雨婷| 边做奶水边喷H高H共妻| JIZZ性欧美2| 又粗又大内射免费视频小说| 国产精品婷婷久久爽一下| 一本久道综合色婷婷五月| 国产福利视频| 精品无码国产一区二区三区AV| 999国产精品999久久久久久| の教室の成熟した女教师| 久久久精品人妻无码专区不卡| 久久影院午夜理论片无码| 国产裸体美女永久免费无遮挡| 大肥波BBWWHBBWW| 公妇借种乱H日出水了| 日本特黄特色aaa大片免费| 欧美大荫蒂AV高潮| 国产精品色情国产三级金瓶双艳| 熟睡人妻被讨厌的公侵犯|