吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
亚洲国产成人精品无码区二本,亚洲AV无码久久寂寞少妇,亚洲色婷婷一区二区三区
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-KALRN/PE-Cy7 Conjugated antibody (bs-11861R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11861R-PE-Cy7
英文名稱1 Rabbit Anti-KALRN/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的舞蹈癥相關(guān)蛋白KALRN抗體
別    名 Duo; FLJ16443; HAPIP; Huntingtin associated protein interacting protein (duo) ; Huntingtin-associated protein-interacting protein; Kalirin (isoform 2); Kalirin; KALRN ; KALRN_HUMAN ; Protein Duo; RhoGEF kinase; Serine/threonine kinase with Dbl and pleckstrin homology domains ; Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain; TRAD.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  神經(jīng)生物學  信號轉(zhuǎn)導(dǎo)  生長因子和激素  激酶和磷酸酶  細胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 340kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KALRN/Duo
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
HAP1 (huntingtin-associated protein 1) binds to huntingtin. Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region. HAP1 shows neuronal localization and moves with huntingtin in nerve fibers. HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem. Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons. Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.

Function:
Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.

Subunit:
Interacts with the C-terminal of peptidylglycine alpha-amidating monooxygenase (PAM) and with the huntingtin-associated protein 1 (HAP1) (By similarity). Interacts with FASLG.

Subcellular Location:
Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with the cytoskeleton.

Tissue Specificity:
Isoform 2 is brain specific. Highly expressed in cerebral cortex, putamen, amygdala, hippocampus and caudate nucleus. Weakly expressed in brain stem and cerebellum. Isoform 4 is expressed in skeletal muscle.

Post-translational modifications:
Autophosphorylated.

DISEASE:
Genetic variation in KALRN is associated with susceptibility to coronary heart disease type 5 (CHDS5) [MIM:608901]. CHD is the leading cause of death and disability worldwide. CHD is multifactorial disease with a strong genetic component. Classic epidemiologic studies have revealed many risk factors for CHD, including age, sex, hypertension, dyslipidemia, diabetes mellitus, smoking, and physical inactivity.

Similarity:
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Contains 1 CRAL-TRIO domain.
Contains 2 DH (DBL-homology) domains.
Contains 1 fibronectin type-III domain.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 2 PH domains.
Contains 1 protein kinase domain.
Contains 2 SH3 domains. Contains 5 spectrin repeats.

Database links:

Entrez Gene: 8997 Human

Entrez Gene: 545156 Mouse

Entrez Gene: 84009 Rat

Omim: 604605 Human

SwissProt: O60229 Human

SwissProt: A2CG49 Mouse

SwissProt: P97924 Rat

Unigene: 8004 Human

Unigene: 353103 Mouse

Unigene: 450612 Mouse

Unigene: 82274 Mouse

Unigene: 87882 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
a级大胆欧美人体大胆666| 挺进绝色邻居的紧窄小肉| 国产精品爽黄69天堂A片潘金莲| 高潮VPSWINDOWS国产乱| 男女裸体做爰爽爽全过程| 精品无码AV一区二区三区不卡| 野外做受又硬又粗又大视频√| 性做爰高清视频在线观看视频| 久久久久久99AV无码免费网站| 天堂VA蜜桃一区二区三区| 粉嫩小泬无遮挡久久久久久| 久久精品国产久精国产| 亚洲精品色午夜无码专区日韩 | 亚洲精品无码久久久久 | 国产精品视频在线观看| CHINESE性内射高清国产| 国产精品久久久久久一区二区三区| 精品人妻人人做人人爽| 丰满雪白人妻人爽AV精品| 草色噜噜噜AV在线观看香蕉| 能收黄台的APP不收费| 国产真人免费无码AV在线观看 | 国产免费观看久久黄AV片| 少妇BBW搡BBBB搡BBBB| 国产偷窥盗拍丰满老熟女| 久久人妻少妇嫩草AV蜜桃| 精品国产污污免费网站入口| 亚洲国产精品18久久久久久| 爱的色放在线播放| 国产AV国片偷人妻麻豆| 一本久道中文无码字幕AV| 久久久久久99AV无码免费网站| 亚洲人成无码网站久久99热国产| 欧美性大战XXXXX久久久| 国产亚洲精品综合一区| 久久国产加勒比精品无码| 狠狠躁18三区二区一区| 日韩精品一区二区亚洲AV| 日韩久久无码免费毛片软件| 野外吮她的花蒂两男一女| 国产麻豆剧传媒精品国产AV|