| 產(chǎn)品編號(hào) | bs-11921R-BF488 |
| 英文名稱1 | Rabbit Anti-GATAD1/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的眼發(fā)育相關(guān)基因蛋白ODAG抗體 |
| 別 名 | ODAG; GATA zinc finger domain containing 1; Ocular development associated gene; GATA zinc finger domain-containing protein 1; ocular development-associated gene protein; GATAD1 protein; ocular development associated; ODAG; RG083M05.2; tcag7.279; GATD1_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 生長因子和激素 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 29kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GATAD1/ODAG |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] Function: ODAG (Ocular development-associated gene), a novel transcription factor located on chromosome 7, encodes a protein that may play a role in eye development. mRNA profiling in multiple human tissue indicates that ODAG is expressed in human CD56+ NK cells and thyroid tissue. Subunit: Component of a chromatin complex, at least composed of KDM5A, GATAD1 and EMSY. Subcellular Location: Nuclear Tissue Specificity: Ubiquitously expressed among various tissue types. Expressed in left ventricular myocytes. DISEASE: Defects in GATAD1 are the cause of cardiomyopathy, dilated type 2B (CMD2B) [MIM:614672]. CMD2B is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. Similarity: Contains 1 GATA-type zinc finger. Database links: Entrez Gene: 57798 Human Entrez Gene: 67210 Mouse SwissProt: Q8N5Y5 Human SwissProt: Q8WUU5 Human SwissProt: Q3TS14 Mouse SwissProt: Q8VCQ2 Mouse SwissProt: Q920S3 Mouse SwissProt: Q9CSG2 Mouse Unigene: 21145 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
