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Rabbit Anti-GATAD1/BF594 Conjugated antibody (bs-11921R-BF594)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-11921R-BF594
英文名稱1 Rabbit Anti-GATAD1/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的眼發(fā)育相關(guān)基因蛋白ODAG抗體
別    名 ODAG; GATA zinc finger domain containing 1; Ocular development associated gene; GATA zinc finger domain-containing protein 1; ocular development-associated gene protein; GATAD1 protein; ocular development associated; ODAG; RG083M05.2; tcag7.279; GATD1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GATAD1/ODAG
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]

Function:
ODAG (Ocular development-associated gene), a novel transcription factor located on chromosome 7, encodes a protein that may play a role in eye development. mRNA profiling in multiple human tissue indicates that ODAG is expressed in human CD56+ NK cells and thyroid tissue.

Subunit:
Component of a chromatin complex, at least composed of KDM5A, GATAD1 and EMSY.

Subcellular Location:
Nuclear

Tissue Specificity:
Ubiquitously expressed among various tissue types. Expressed in left ventricular myocytes.

DISEASE:
Defects in GATAD1 are the cause of cardiomyopathy, dilated type 2B (CMD2B) [MIM:614672]. CMD2B is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Similarity:
Contains 1 GATA-type zinc finger.

Database links:

Entrez Gene: 57798 Human

Entrez Gene: 67210 Mouse

SwissProt: Q8N5Y5 Human

SwissProt: Q8WUU5 Human

SwissProt: Q3TS14 Mouse

SwissProt: Q8VCQ2 Mouse

SwissProt: Q920S3 Mouse

SwissProt: Q9CSG2 Mouse

Unigene: 21145 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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