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Rabbit Anti-GABRR1/BF488 Conjugated antibody (bs-12084R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12084R-BF488
英文名稱1 Rabbit Anti-GABRR1/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的G氨基丁酸A型受體rho1/GABAA Rρ1抗體
別    名 bA135P14.1 (gamma-aminobutyric acid (GABA) receptor rho 1); GABA(A) receptor subunit rho-1; gamma aminobutyric acid receptor rho 1; gamma-aminobutyric acid (GABA) A receptor rho-1; gamma-aminobutyric acid (GABA) receptor rho 1; Gamma-aminobutyric acid receptor subunit rho-1; MGC163216; GBRR1_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  通道蛋白  細(xì)胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABRR1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Function:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand gated chloride channels. GABRR1 is a member of the rho subunit family

Subunit:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1

Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane; Multipass membrane protein. Cell membrane; Multipass membrane protein.

Tissue Specificity:
Highly expressed in the retina and in a lesser extent in brain, lung and thymus.

Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily.

Database links:

Entrez Gene: 2569 Human

Omim: 137161 Human

SwissProt: P24046 Human

Unigene: 99927 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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