吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
草草久久久无码国产专区,古代妓院做爰片120分钟
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-KCNQ2/BF555 Conjugated antibody (bs-11728R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11728R-BF555
英文名稱1 Rabbit Anti-KCNQ2/BF555 Conjugated antibody
中文名稱 BF555標記的鉀離子通道蛋白家族KCNQ2抗體
別    名 BFNC; BFNS1; EBN 1; EBN; EBN1; EIEE7; ENB 1; ENB1; HNSPC; KCNA 11; KCNA11; KCNQ 2; Kcnq2; KCNQ2_HUMAN; KQT like 2; KQT-like 2; KV7.2; KVEBN 1; KVEBN1; KvLQT 2; KvLQT2; Neuroblastoma specific potassium channel alpha subunit KvLQT2; Neuroblastoma specific potassium channel protein; Neuroblastoma specific potassium channel subunit alpha; Neuroblastoma specific potassium channel subunit alpha KvLQT2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Potassium voltage gated channel KQT like protein 2; Potassium voltage gated channel KQT like subfamily member 2; Potassium voltage gated channel subfamily KQT member 2; Potassium voltage-gated channel subfamily KQT member 2; Voltage gated potassium channel subunit Kv7.2; Voltage-gated potassium channel subunit Kv7.2.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學  通道蛋白  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 96kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCNQ2 (91-150aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Epilepsy affects about 0.5% of the world’s population and has a large genetic component. Epilepsy results from an electrical hyperexcitability in the central nervous system. Potassium channels are important regulators of electrical signaling, determining the firing properties and responsiveness of a variety of neurons. Benign familial neonatal convulsions (BFNC), an autosomal dominant epilepsy of infancy, has been shown to be caused by mutations in the KCNQ2 or the KCNQ3 potassium channel genes. KCNQ2 and KCNQ3 are voltage-gated potassium channel proteins with six putative transmembrane domains. Both proteins display a broad distribution within the brain, with expression patterns that largely overlap.

Function:
Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. KCNQ2/KCNQ3 current is blocked by linopirdine and XE991, and activated by the anticonvulsant retigabine. Muscarinic agonist oxotremorine-M strongly suppress KCNQ2/KCNQ3 current in cells in which cloned KCNQ2/KCNQ3 channels were coexpressed with M1 muscarinic receptors.

Subunit:
Heteromultimer with KCNQ3. May associate with KCNE2.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
In adult and fetal brain. Highly expressed in areas containing neuronal cell bodies, low in spinal chord and corpus callosum. Isoform 2 is preferentially expressed in differentiated neurons. Isoform 6 is prominent in fetal brain, undifferentiated neuroblastoma cells and brain tumors.

Post-translational modifications:
In Xenopus oocytes KCNQ2/KCNQ3 heteromeric current can be increased by intracellular cyclic AMP, an effect that depends on phosphorylation of Ser-52 in the N-terminus region.

DISEASE:
Defects in KCNQ2 are the cause of benign familial neonatal seizures type 1 (BFNS1) [MIM:121200]. A disorder characterized by clusters of seizures occurring in the first days of life. Most patients have spontaneous remission by 12 months of age and show normal psychomotor development. Some rare cases manifest an atypical severe phenotype associated with epileptic encephalopathy and psychomotor retardation. The disorder is distinguished from benign familial infantile seizures by an earlier age at onset. In some patients, neonatal convulsions are followed later in life by myokymia, a benign condition characterized by spontaneous involuntary contractions of skeletal muscles fiber groups that can be observed as vermiform movement of the overlying skin. Electromyography typically shows continuous motor unit activity with spontaneous oligo- and multiplet-discharges of high intraburst frequency (myokymic discharges). Some patients may have isolated myokymia. Defects in KCNQ2 are the cause of epileptic encephalopathy early infantile type 7 (EIEE7) [MIM:613720]. EIEE7 is an autosomal dominant seizure disorder characterized by infantile onset of refractory seizures with resultant delayed neurologic development and persistent neurologic abnormalities.

Similarity:
Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.2/KCNQ2 sub-subfamily.

Database links:

Entrez Gene: 3785 Human

Entrez Gene: 16536 Mouse

Entrez Gene: 170848 Rat

Omim: 602235 Human

SwissProt: O43526 Human

SwissProt: Q9Z351 Mouse

SwissProt: O88943 Rat

Unigene: 161851 Human

Unigene: 40615 Mouse

Unigene: 440175 Mouse

Unigene: 33317 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
永久免费精品精品永久-夜色| 成年免费a级毛片免费看无码| 国产成人无码A区在线观看视频 | 亚洲精品AV中文字幕在线| 全免费A级毛片免费看网站| 男受被做哭激烈娇喘GV视频| PORNO日本| 99久久国产热无码精品免费 | japanese成熟丰满熟妇| 国产97色在线 | 国产| 蜜臀AV在线播放一区二区三区| 国产大片B站免费观看推荐| 国产日产久久高清欧美一区| 嗯灬啊灬把腿张开灬A片小说| 精品熟人妻一区二区三区四区不卡 | 免费无码国产V片在线观看 | 国产性生交XXXXX免费| 又硬又粗又大一区二区三区视频| 成人免费视频一区二区| 99国产精品国产精品九九| 秋霞成人午夜鲁丝一区二区三区| 久久久精品人妻无码专区不卡| 最近免费中文字幕中文高清百度 | 少妇扒开粉嫩小泬视频| 在线观看的AV网站| 国产亚洲精品一区二区在线观看| 麻豆传媒视频| 国产精品永久免费视频| 国产成人精品免高潮在线观看| 人物动物交互狗AA| 亚洲欧美日韩精品久久亚洲区| 国产又粗又猛又爽又黄| 人妻AV无码一区二区三区| 国产精品毛片无码| 精品无码久久久久久国产| 国产精品视频在线观看| 696969大但人文艺术正道| 日日碰狠狠添天天爽无码| 久久夜色精品国产噜噜亚洲av | 久久久久久99AV无码免费网站| 亚洲精品又粗又大又爽A片|