產(chǎn)品編號 | bs-13824R-BF555 |
英文名稱1 | Rabbit Anti-CECR2/BF555 Conjugated antibody |
中文名稱 | BF555標(biāo)記的貓眼綜合征染色體候選基因2抗體 |
別 名 | Cat eye syndrome chromosome region candidate 2; CECR2_HUMAN; KIAA1740. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul |
研究領(lǐng)域 | 細胞生物 免疫學(xué) 細菌及病毒 結(jié)合蛋白 細胞表面分子 淋巴細胞 t-淋巴細胞 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, (predicted: Mouse, Rat, Chicken, Dog, Horse, ) |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 59/164kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CECR2 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. This family consists of several mammalian T-cell surface antigen CD2 proteins as well as homologous African swine fever virus sequences. Function: Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis. Subunit: Part of the CECR2-containing remodeling factor (CERF) complex which contains CECR2 and SMARCA1. Interacts with acetylated lysine residues on histone H2A and H3 (in vitro). Interacts with LRPPRC. Tissue Specificity: Highly expressed in skeletal muscle, thymus, placenta and lung. Expressed at lower level in brain, heart, colon, spleen, kidney. Similarity: Contains 1 bromo domain. Database links: Entrez Gene: 27443 Human Omim: 607576 Human SwissProt: Q9BXF3 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |