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Rabbit Anti-ZNF516/AP Conjugated antibody (bs-12238R-AP)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12238R-AP
英文名稱1 Rabbit Anti-ZNF516/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的鋅指蛋白516抗體
別    名 C330029B10Rik; D230016L03; HsT287; RGD1306817; Zfp26l; zinc-finger protein 516; Zinc finger protein 516; ZN516_HUMAN; Znf516.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 轉(zhuǎn)錄調(diào)節(jié)因子  鋅指蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 124kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human ZNF516
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF516 is a 1,163 amino acid nuclear protein that contains ten C2H2-type zinc-fingers. The gene encoding ZNF516 maps to human chromosome 18, in a region that is frequently found to be affected in 18q deletion syndrome, a multiple-anomaly mental retardation syndrome that is associated with congenital aural atresia.

Function:
May be involved in transcriptional regulation.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 10 C2H2-type zinc fingers.

Database links:
UniProtKB/Swiss-Prot: Q92618.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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