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Rabbit Anti-CORO7/Biotin Conjugated antibody (bs-13999R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13999R-Bio
英文名稱1 Rabbit Anti-CORO7/Biotin Conjugated antibody
中文名稱 生物素標記的肌動蛋白結合蛋白7抗體
別    名 Clipin-E; CORO6; CORO7_HUMAN; Coronin, actin binding protein 6; Coronin-6; Coronin-like protein E; FLJ14871; PP1009; PP1782; PP1881.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  轉運蛋白  結合蛋白  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 101kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CORO7
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Coronins, such as CORO7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins. CORO7 plays a role in Golgi complex morphology and function (Rybakin et al., 2004, 2006 [PubMed 15327992] [PubMed 16905771]).[supplied by OMIM, Mar 2008]

Function:
May play a role in the maintenance of the Golgi apparatus morphology and in the protein export from the Golgi.

Subcellular Location:
Cytoplasm > cytosol. Golgi apparatus membrane. Cytoplasmic vesicle. Predominantly cytosolic. Detected on vesicle-like cytoplasmic structures and on the cis-Golgi. Not associated with actin filaments.

Post-translational modifications:
The membrane-associated form is phosphorylated on tyrosine residues.

Similarity:
Belongs to the WD repeat coronin family.
Contains 8 WD repeats.

Database links:

Entrez Gene: 79585 Human

Entrez Gene: 78885 Mouse

Entrez Gene: 192276 Rat

Omim: 611668 Human

SwissProt: P57737 Human

SwissProt: Q9D2V7 Mouse

SwissProt: O35828 Rat

Unigene: 437957 Human

Unigene: 325512 Mouse

Unigene: 13808 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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