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Rabbit Anti-ACCN4/PE-Cy5.5 Conjugated antibody (bs-12129R-PE-Cy5.5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12129R-PE-Cy5.5
英文名稱1 Rabbit Anti-ACCN4/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的腦鈉通道蛋白4抗體
別    名 Accn4; ACCN4_HUMAN; Acid sensing (proton gated) ion channel family member 4; Acid sensing ion channel 4; Acid-sensing ion channel 4; Amiloride sensitive cation channel 4; Amiloride sensitive cation channel 4 pituitary; Amiloride sensitive cation channel family member 4 pituitary; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4; ASIC4; BNAC4; Brain sodium channel 4; pituitary.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  通道蛋白  細(xì)胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACCN4/ASIC4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012].

Function:
Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.

Subunit:
Homotrimer or heterotrimer with other ASIC proteins.

Subcellular Location:
.Membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti.

Similarity:
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ACCN4 subfamily.

Database links:

Entrez Gene: 55515 Human

Entrez Gene: 241118 Mouse

Entrez Gene: 63882 Rat

Omim: 606715 Human

SwissProt: Q96FT7 Human

SwissProt: Q7TNS7 Mouse

SwissProt: Q9JHS6 Rat

Unigene: 87469 Human

Unigene: 110790 Mouse

Unigene: 44831 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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