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Rabbit Anti-Troponin I fast + slow skeletal muscle /BF594 Conjugated antibody (bs-10617R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-10617R-BF594
英文名稱1 Rabbit Anti-Troponin I fast + slow skeletal muscle /BF594 Conjugated antibody
中文名稱 BF594標記的骨骼肌快/慢肌肌鈣蛋白I抗體
別    名 AMCD2B; DA2B; DKFZp451O223; Fast twitch skeletal muscle troponin I; FSSV; fsTnI; OTTHUMP00000014141; OTTHUMP00000014142; OTTHUMP00000014143; OTTHUMP00000033877; OTTHUMP00000033909; OTTHUMP00000033910; SSTNI; TNN1; Troponin I fast twitch 2; Troponin I type 1 (skeletal, slow); Troponin I type 2 (skeletal, fast); Troponin I, fast skeletal muscle; Troponin I, fast twitch isoform; Troponin I, fast twitch skeletal muscle isoform; Troponin I, skeletal, fast; Troponin I, slow skeletal muscle; Troponin I, slow twitch isoform; TNNI1_HUMAN; TNNI2_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 33kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNNI1+TNNI2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue.

Function:
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Subunit:
Binds to actin and tropomyosin.

DISEASE:
Arthrogryposis, distal, 2B (DA2B) [MIM:601680]: A form of distal arthrogryposis, a disease characterized by congenital joint contractures that mainly involve two or more distal parts of the limbs, in the absence of a primary neurological or muscle disease. DA2B is characterized by contractures of the hands and feet, and a distinctive face characterized by prominent nasolabial folds, small mouth and downslanting palpebral fissures. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the troponin I family.

Database links:

Entrez Gene: 7135 Human

Entrez Gene: 7136 Human

Omim: 191042 Human

Omim: 191043 Human

SwissProt: P19237 Human

SwissProt: P48788 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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