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Rabbit Anti-Cytochrome P450 2B1/AP Conjugated antibody (bs-14177R-AP)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-14177R-AP
英文名稱1 Rabbit Anti-Cytochrome P450 2B1/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的細(xì)胞色素P450 2B1抗體
別    名 Cyp2b 1; Cyp2b 2; Cyp2b1; Cyp2b2; Cypbe; Cytochrome P450 2B1 + 2B2; Cype; CYPIIB1; CYPIIB2; Cytochrome P 450b; Cytochrome P 450b type e; Cytochrome P 450e M; Cytochrome P450 2B1; Cytochrome P450 2B2; Cytochrome P450 family 2 subfamily b polypeptide 1; Cytochrome P450 family 2 subfamily b polypeptide 2; Cytochrome P450 subfamily IIB phenobarbital inducible b e; ec 1.14.14.1; P450 PB4; P450-B; P450-LM2; P450-PB1 and P450-PB2; P450b; P450E; CP2B1_RAT.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  心血管  細(xì)胞生物  新陳代謝  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Mouse, Rat, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Rat Cytochrome P450 2B1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
phenobarbitol-inducible member of the p450 xenobiotic-inducible superfamily involved in hydroxylation of decanoic and other fatty acids [RGD, Feb 2006]

Function:
The Cytochrome P450 superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.

Subcellular Location:
Membrane bound, endoplasmic reticulum

Post-translational modifications:
Phosphorylation is accompanied by a decrease in enzyme activity.

Similarity:
Belongs to the cytochrome P450 family.

Database links:

Entrez Gene: 24300 Rat

Entrez Gene: 361523 Rat

SwissProt: P00176 Rat

SwissProt: P04167 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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