產(chǎn)品編號 | bs-14219R-Gold |
英文名稱1 | Rabbit Anti-DDX24/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的ATP依賴解旋酶DDX24抗體 |
別 名 | ATP dependent RNA helicase DDX24; ATP-dependent RNA helicase ddx24; DDX 24; ddx24; DDX24_HUMAN; DEAD (Asp Glu Ala Asp) box polypeptide 24; DEAD box protein 24; DEAD/H (Asp Glu Ala Asp) box polypeptide 24; S. cerevisiae CHL1 like helicase. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 心血管 細(xì)胞生物 神經(jīng)生物學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 120kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DDX24 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level. [provided by RefSeq, Jul 2008] Function: ATP-dependent RNA helicase. Tissue Specificity: Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Database links: Entrez Gene: 57062 Human Entrez Gene: 27225 Mouse Omim: 606181 Human SwissProt: Q9GZR7 Human SwissProt: Q9ESV0 Mouse Unigene: 510328 Human Unigene: 3935 Mouse Unigene: 475067 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |