| 產(chǎn)品編號 | bs-14292R-Gold |
| 英文名稱1 | Rabbit Anti-DGCR14/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的狄喬治(DiGeorge)氏綜合征相關(guān)蛋白抗體 |
| 別 名 | DGCR14; DGS H; DGS I; DGSH; DGSI; DiGeorge syndrome critical region gene 14; DiGeorge syndrome critical region gene DGSI; DiGeorge syndrome critical region protein 14; DiGeorge syndrome gene H; DiGeorge syndrome gene I; ES2; DGC14_HUMAN； ES2 protein; Es2el. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 心血管 發(fā)育生物學(xué) 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 53kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DGCR14 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: DGCR14 is a 476 amino acid nuclear protein that belongs to the DGCR14 family. DGCR14 is believed to play a part in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. Most cases result from a deletion of chromosome 22q11.2 (DiGeorge syndrome chromosome region, or DGCR). This protein localizes to the nucleus and co-purifies with C complex spliceosomes. Function: DiGeorge syndrome critical region 14, DGCR14 has been identified in the spliceosome C complex and may be involved in pre-mRNA splicing. May have a role in velocardiofacial/DiGeorge syndrome (VCFS/DGS), a developmental disorder characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and facial anomalies. Most cases of this syndrome involve a deletion of chromosome 22q11.2 in the DiGeorge syndrome chromosome region. Subcellular Location: Nuclear Similarity: Belongs to the DGCR14 family. Database links: Entrez Gene: 8220 Human Omim: 601755 Human SwissProt: Q96DF8 Human Unigene: 517407 Human Unigene: 686112 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
