| 產(chǎn)品編號 | bs-12465R-RBITC |
| 英文名稱1 | Rabbit Anti-Alpha SNAP/RBITC Conjugated antibody |
| 中文名稱 | 羅丹明（RBITC）標(biāo)記的可溶性附著蛋白α-SNAP抗體 |
| 別 名 | Alpha soluble NSF attachment protein; Alpha-soluble NSF attachment protein; N ethylmaleimide sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; NAPA; SNAA_HUMAN; SNAP alpha; SNAP alpha; SNAP-alpha; SNAPA. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)運蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 33kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Alpha SNAP |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs (also designated synaptobrevins), including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Subunit: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8 (By similarity). Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12 (By similarity). Subcellular Location: Membrane; Peripheral membrane protein. Similarity: Belongs to the SNAP family. Database links: Entrez Gene: 8775 Human Entrez Gene: 108124 Mouse Omim: 603215 Human SwissProt: P54920 Human SwissProt: Q9DB05 Mouse Unigene: 126938 Human Unigene: 727492 Human Unigene: 104540 Mouse Unigene: 431371 Mouse Unigene: 31745 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
