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Rabbit Anti-NAV3/APC Conjugated antibody (bs-12151R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12151R-APC
英文名稱1 Rabbit Anti-NAV3/APC Conjugated antibody
中文名稱 APC標記的神經元引導蛋白3抗體
別    名 KIAA0938; NAV 3; NAV3; NAV3_HUMAN; Neuron navigator 3; POMFIL1; Pore membrane and/or filament-interacting-like protein 1; Steerin 3; Steerin-3; STEERIN3; Unc 53 homolog 3; Unc-53 homolog 3; unc53H3.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 255kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NAV3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
May regulate IL2 production by T-cells. May be involved in neuron regeneration.

Function:
May regulate IL2 production by T-cells. May be involved in neuron regeneration.

Subcellular Location:
Nucleus outer membrane.

Tissue Specificity:
Highly expressed in brain. Expressed at low levels in heart and placenta. Present in activated T-cells but not in resting T-cells (at protein level). Down-regulated in primary neuroblastoma.

DISEASE:
Note=A chromosomal aberration disrupting NAV3 has been found in patients with Sezary syndrome. Translocation t(12;18)(q21;q21.2).

Similarity:
Sequence similarities; Belongs to the Nav/unc-53 family.
Contains 1 CH (calponin-homology) domain.

Database links:

Entrez Gene: 89795 Human

Entrez Gene: 260315 Mouse

Entrez Gene: 314814 Rat

Omim: 611629 Human

SwissProt: Q8IVL0 Human

SwissProt: Q80TN7 Mouse

Unigene: 655301 Human

Unigene: 225050 Mouse

Unigene: 394160 Mouse

Unigene: 461280 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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