產(chǎn)品編號 | bs-12478R-BF350 |
英文名稱1 | Rabbit Anti-Annexin A13/BF350 Conjugated antibody |
中文名稱 | BF350標(biāo)記的膜粘連蛋白13抗體 |
別 名 | Annexin A13; Annexin XIII; Annexin, intestine-specific; Annexin-13; ANX 13; ANX A13; ANX13; ANX13_HUMAN; ANXA13; Intestine Specific Annexin; Intestine-specific annexin; ISA; MGC150460. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 通道蛋白 細(xì)胞粘附分子 細(xì)胞膜蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 35kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Annexin A13 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The Annexins constitute a family of structurally-related, relatively abundant proteins that exhibit Ca2+-dependent binding to phospholipids. Annexins function in multiple aspects of cell biology including regulation of membrane trafficking, transmembrane channel activity, inhibition of phospholipase A2, inhibition of coagulation and mediation of cell-matrix interactions. Annexin A13 is considered the original progenitor of the 12 members of vertebrate Annexins. The expression of Annexin A13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Two alternative splicing isoforms of Annexin A13 exist, both of which bind to rafts. Subcellular Location: Cell membrane. Associated with the plasma membrane of undifferentiated, proliferating crypt epithelial cells as well as differentiated villus enterocytes. Tissue Specificity: Gut specific. Similarity: Belongs to the annexin family. Contains 4 annexin repeats. Database links: Entrez Gene: 312 Human Entrez Gene: 69787 Mouse Omim: 602573 Human SwissProt: P27216 Human SwissProt: Q99JG3 Mouse Unigene: 181107 Human Unigene: 237985 Mouse Unigene: 100125 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |