吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
欧洲人妻丰满AV无码久久不卡,成人免费无遮挡无码黄漫视频
Rabbit Anti-DCP1A/PE-Cy5 Conjugated antibody (bs-12986R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12986R-PE-Cy5
英文名稱1 Rabbit Anti-DCP1A/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的脫帽酶1A抗體
別    名 DCP1 decapping enzyme homolog A; Dcp1a; DCP1A_HUMAN; mRNA decapping enzyme 1A; mRNA-decapping enzyme 1A; Smad4 interacting transcriptional co activator; Smad4-interacting transcriptional co-activator; Smad4-interacting transcriptional co-activator; SMAD4IP1; SMIF; Transcription factor SMIF.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 63kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DCP1A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Cleavage of the 5'-cap structure is involved in the major 5'-to-3' and nonsense-mediated mRNA decay pathways. The protein complex consisting of Dcp1 and Dcp2 has been identified as the species responsible for the decapping reaction in Saccharomyces cerevisiae. In nonsense-mediated decay, the human decapping complex, made up of S. cerevisiae homologs hDcp1a and hDcp2, may be recruited to mRNAs containing premature termination codons by nonsense-mediated decay factor (Upf) proteins. hDcp2 specifically hydrolyzes methylated capped RNA to release m(7)GDP, thereby aiding in mRNA degradation. Both hDcp1a and hDcp2 colocalize in the cytoplasm. In addition, hDcp1a interacts with Smad4 forming a complex with TGF Beta and BMP-4. hDcp1a and Smad4 interact directly through a EVH1/WH1 domain on hDcp1a and a proline-rich activation domain on Smad4. Smad4 is essential to nuclear translocation of hDcp1a as deletion of the Smad4-interacting domain (located in the N-terminal 100 amino acids) of hDcp1a eliminates TGF Beta-induced nuclear translocation of hDcp1a.

Function:
Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.

Subunit:
Forms a complex with EDC3, DCP2, DDX6 and EDC4/HEDLS, within this complex directly interacts with EDC3. Binds DCP1B, UPF1 and SMAD4. Part of a cytoplasmic complex containing proteins involved in mRNA decay, including XRN1 and LSM1. Interacts with PNRC2. Interacts with DDX17 in an RNA-independent manner. Interacts with ZC3HAV1.

Subcellular Location:
Cytoplasm, P-body. Nucleus. Co-localizes with NANOS3 in the processing bodies. Predominantly cytoplasmic, in processing bodies (PB). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4.

Tissue Specificity:
Detected in heart, brain, placenta, lung, skeletal muscle, liver, kidney and pancreas.

Similarity:
Belongs to the DCP1 family.

Database links:
UniProtKB/Swiss-Prot: Q9NPI6.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
特黄三级又爽又粗又大| 肉大捧一进一出免费视频 | 久久久无码精品亚洲日韩啪啪网站 | 精品无码国产一区二区三区麻豆| 久久99精品久久久久婷婷| 大陆熟妇丰满多毛XXXX| 黑人巨大精品欧美一区二区免费| 日本又色又爽又黄的A片18禁 | 日本无遮挡边做边爱边摸| 大又大又粗又硬又爽少妇毛片| 国产SUV精品一区二人妻| 亚洲AV无码国产一区二区三区| 女人被狂躁的高潮免费视频| AV大片| 全部孕妇毛片丰满孕妇孕交| 国产SUV精品一区二区| 亚洲AV无一区二区三区| 久久精品国产99国产精品导航| 日韩三级| 天天做天天爱夜夜爽毛片毛片,| 欧美电影在线观看| 中文字幕一区二区| 精品人妻无码一区二区三区绿| 欧美,日韩,国产,专区| 性高湖久久久久久久久| 免费A级毛片黄A片高清在线播放 | 亚洲 欧美 叧类人妖| 全免费A级毛片免费看网站 | ,国产精品久久久久久| 色一情一乱一伦一区二区三区 | 双性美人被调教到喷水A片| 国产精品VA在线观看无码不卡| 熟妇人妻中文字幕无码老熟妇| 天天躁日日躁AAAAXXXX| 日韩精品一区二区亚洲AV观看 | 精品夜夜澡人妻无码AV蜜桃| 国产在线视频一区二区三区 | 丝袜美腿一区二区三区| 国产成人精品A视频一区| 国内揄拍国内精品少妇国语| 欧洲亚洲国产精华液|