吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線(xiàn):400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  人才招聘  關(guān)于我們  聯(lián)系我們
熟妇女人妻丰满少妇中文字幕,一边喘气一边叫疼的视频
Rabbit Anti-KDM1/LSD1/PE-Cy7 Conjugated antibody (bs-10166R-PE-Cy7)
訂購(gòu)熱線(xiàn):400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-10166R-PE-Cy7
英文名稱(chēng)1 Rabbit Anti-KDM1/LSD1/PE-Cy7 Conjugated antibody
中文名稱(chēng) PE-Cy7標(biāo)記的組蛋白賴(lài)氨酸特異性脫甲基酶1抗體
別    名 Amine oxidase (flavin containing) domain 2; Amine oxidase flavin containing domain 2; Amine oxidase flavin containing domain protein 2; AOF 2; AOF2; BHC110; BRAF35 HDAC complex protein BHC110; BRAF35-HDAC complex protein BHC110; FAD binding protein BRAF35 HDAC complex, 110 kDa subunit; Flavin containing amine oxidase domain containing protein 2; Flavin-containing amine oxidase domain-containing protein 2; KDM 1; Kdm1a; KDM1A_HUMAN; KIAA0601; LSD 1; LSD1; Lysine (K) specific demethylase 1; Lysine (K) specific demethylase 1A; Lysine specific histone demethylase 1; Lysine specific histone demethylase 1A; Lysine-specific histone demethylase 1; Lysine-specific histone demethylase 1A.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  染色質(zhì)和核信號(hào)  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 94kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KDM1
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Gene activation and repression is specifically regulated by histone methylation status at distinct lysine residues. Lysine specific demethylase 1 (KDM1/LSD1) is a long-sought histone demethylase that specifically demethylates mono and di methyl histone H3 at K4 and K9. Thus KDM1 is a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.

Function:
Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity. Also acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and mediating demethylation of H3K9me, a specific tag for epigenetic transcriptional repression. The presence of PRKCB in ANDR-containing complexes, which mediates phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag that prevents demethylation H3K4me, prevents H3K4me demethylase activity of KDM1A. Demethylates di-methylated 'Lys-370' of p53/TP53 which prevents interaction of p53/TP53 with TP53BP1 and represses p53/TP53-mediated transcriptional activation. Demethylates and stabilizes the DNA methylase DNMT1. Required for gastrulation during embryogenesis. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development.

Subunit:
Component of a RCOR/GFI/KDM1A/HDAC complex. Interacts directly with GFI1 and GFI1B (By similarity). Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B, KDM1A, RCOR1 and PHF21A. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. In the complex, RCOR1/CoREST strongly enhances the demethylase activity and protects it from the proteasome while PHF21A/BHC80 inhibits the demethylase activity. Interacts with the androgen receptor (AR). Interacts with ASXL1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the flavin monoamine oxidase family.
Contains 1 SWIRM domain.

Database links:

Entrez Gene: 23028 Human

Entrez Gene: 99982 Mouse

Entrez Gene: 500569 Rat

Omim: 609132 Human

SwissProt: O60341 Human

SwissProt: Q6ZQ88 Mouse

Unigene: 591518 Human

Unigene: 28540 Mouse

Unigene: 203461 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.xucheq.com 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
中文字幕人妻丝袜乱一区三区| 国产精品成熟老女人| 亚洲AV无码成人黄网站在线观看| 14表妺好紧没带套18分钟| 肉色欧美久久久久久久蜜桃| 14妺妺让我破了她的处| 性少妇FREESEXVIDEOS高清| 成人AAA片一区国产精品| 免费a级黄毛片| 色综合天天综合网国产成人网| 精品人妻无码一区二区三区,| 久久久国产精华液| 久久精品国产99国产精品导航| 99久久精品国产一区二区三区| 免费A级毛片做爰片在线| 亚洲国产成人精品无码区二本| 国产精品无码专区AV在线播放| 欧美精品久久96人妻无码| 一本一道久久A久久精品综合| 国产精品免费看久久久无码| 久久人妻少妇嫩草AV无码专区| 国产免费av片在线无码免费看| 大屁股熟女一区二区三区| 国产精品人人爽人人做我的可爱| 老头扒开粉嫩的小缝亲吻| 国产免费又爽又色又粗视频 | 国产AV人人夜夜澡人人爽麻豆| 亚洲日韩国产精品乱-久| 国产精品JIZZ在线观看无码| 无码免费人妻A片AAA毛片一区| 亚洲熟妇AV一区二区三区漫画| 鲁一鲁一鲁一鲁一澡| 久久久久久国产精品免费免费| 国产成人精品亚洲日本在线观看| 国产特黄A片AAAA毛片| 国产精品无码免费专区午夜| 最残忍最另类残虐SM的小说| 18禁裸乳无遮挡啪啪无码免费 | 少妇荡乳情欲办公室456视频| 人妻 丝袜美腿 中文字幕 | 亚洲色大成网站WWW久久九九|