產(chǎn)品編號 | bs-13480R-APC |
英文名稱1 | Rabbit Anti-GOLGA3/APC Conjugated antibody |
中文名稱 | APC標(biāo)記的高爾基體膜相關(guān)蛋白抗體 |
別 名 | GCP170; GOLGA 3; GOLGA3; Golgi autoantigen; Golgi complex associated protein of 170 kDa; Golgi complex-associated protein of 170 kD; Golgi membrane associated protein; Golgi peripheral membrane protein; Golgin 160; Golgin subfamily a 3; HGNC:4426; Male enhanced antigen 2; MEA2; SY2/SY10 protein; GOGA3_HUMAN. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 167kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GOLGA3/Golgin 160 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: The Golgi apparatus consists of a series of stacked, flattened membrane stacks called cisternae that are involved in the transport of lipids and proteins in the secretory pathway and are important for Golgi-microtubule interaction. Golgin 160 is a 1,498 amino acid protein that localizes to both the cytoplasm and to the Golgi apparatus and contains a series of coiled-coil domains. Expressed in a variety of tissues, including heart, liver, testis, kidney, lung and salivary gland, golgin 160 functions as a homodimer that interacts with GOLGA7 and is thought to be involved in maintaining Golgi structure and may play a role in nuclear transport and Golgi apparatus localization. Multiple isoforms of golgin 160 exist due to alternative splicing events. Function: GOLGA3 is a member of the golgin family of proteins which are localized to the Golgi. It has been postulated to play a role in nuclear transport and Golgi apparatus localization. Subunit: Homodimer. Interacts with GOLGA7. Isoform 1 interacts with GOPC while isoform 3 does not. Subcellular Location: Cytoplasmic and Golgi Apparatus. Tissue Specificity: Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney. Post-translational modifications: Cleaved by caspases in apoptotic cells. Database links: Entrez Gene: 2802 Human Omim: 602581 Human SwissProt: Q08378 Human Unigene: 507333 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |