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Rabbit Anti-Golgin subfamily A member 4/Gold Conjugated antibody (bs-13487R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13487R-Gold
英文名稱1 Rabbit Anti-Golgin subfamily A member 4/Gold Conjugated antibody
中文名稱 膠體金標記的高爾基體蛋白A亞基4抗體
別    名 256 kDa golgin; 72.1 protein; GCP2; GOGA4_HUMAN; GOLG; GOLGA4; golgi autoantigen, golgin subfamily a, 4; Golgin subfamily A member 4; golgin-240; Golgin-245; MU-RMS-40.18; OTTHUMP00000161363; OTTHUMP00000208897; OTTHUMP00000209805; p230; Protein 72.1; Trans-Golgi p230; Golgin 245.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 261kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Golgin subfamily A member 4/Golgin 245
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Golgin 245 is also known as p230, GCP2, GOLG or golgi autoantigen and is a 2,230 amino acid protein that is expressed as three isoforms. Golgin 245 is localized to the cytoplasm in cells and is a member of the golgin family, all of which are peripheral membrane proteins associated with the Golgi complex. Golgin 245 has a carboxyl-terminal GRIP domain, which attaches to the trans-Golgi network (TGN) and TGN-derived vesicles. It is thought that the interaction that takes place between golgin 245 and MACF1, which cross-links microtubules to the Actin cytoskeleton, allows proteins to be transported from the TGN to the cell periphery. Antibodies against golgin 245 are associated with two chronic disorders known as Sj鰃ren's syndrome and Hepatitis B.

Function:
May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1.

Subunit:
Homodimer. Interacts with GTP bound ARL1. Interacts with MACF1.

Subcellular Location:
Cytoplasm. Golgi apparatus membrane. Golgi apparatus.

Similarity:
Contains 1 GRIP domain.

Database links:

Entrez Gene: 2803 Human

Omim: 602509 Human

SwissProt: Q13439 Human

Unigene: 344151 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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