吃奶呻吟打开双腿做受动态图 -亚洲色偷偷色噜噜狠狠99网-日韩精品极品视频在线观看免费-来一水AV@lysav

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  人才招聘  關于我們  聯(lián)系我們
日韩一区二区三区精品,久久久无码一区二区三区,黑人巨大精品欧美一区二区
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GGA3/Cy7 Conjugated antibody (bs-13345R-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術支持:techsupport@xucheq.com
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13345R-Cy7
英文名稱1 Rabbit Anti-GGA3/Cy7 Conjugated antibody
中文名稱 Cy7標記的γ-銜接蛋白相關蛋白3抗體
別    名 ADP ribosylation factor binding protein 3; ADP ribosylation factor binding protein GGA 3; ADP ribosylation factor binding protein GGA3; ADP-ribosylation factor-binding protein GGA3; ARF binding protein GGA 3; ARF binding protein GGA3; ARF-binding protein 3; gamma ear-containing; GGA 3; GGA3; GGA3_HUMAN; Golgi associated gamma adaptin ear containing ARF binding protein 3; Golgi localized gamma ear containing ARF binding protein 3; Golgi-localized; KIAA0154.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  轉運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 78kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GGA3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The GGA family of proteins (Golgi-localized, g-Adaptin ear-containing, ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, ARF (ADP-ribosylation factor), and clathrin. Members of the GGA family, GGA1,GGA2 (also known as VEAR) and GGA3, are multi-domain proteins that bind mannose 6-phosphate receptors (MPRs). GGAs have modular structures with an N-terminal VHS (VPS27, Hrs and STAM) domain followed by a GAT (GGA and Tom1) domain, a connecting hinge segment and a C-terminal GAE (g-Adaptin ear) domain. The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences. The human GGA3 gene maps to chromosome 17 and encodes a 723 amino acid protein that shares 46% sequence identity with GGA1 and 38% with GGA2.

Function:
Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.

Subunit:
Monomer. Interacts with SORT1, SORL1, LRP3, GGA binding partner (GGABP) and P200 (By similarity). Interacts with GGA1 and GGA2. Binds to clathrin and activated ARFs. Binds RABEP1 and RABGEF1. Interacts with the membrane proteins M6PR/CD-MPR, IGF2R/CI-MPR and BACE1 and the accessory proteins SYNRG, EPN4, NECAP1, NECAP2 and AFTPH/aftiphilin. Interacts with TSG101 and UBC.

Subcellular Location:
Golgi apparatus; trans-Golgi network membrane. Endosome membrane.

Tissue Specificity:
Ubiquitously expressed.

Post-translational modifications:
Phosphorylated by CK2 and dephosphorylated by PP2A (By similarity). Phosphorylation of GGA3 allows the internal AC-LL motif to bind the VHS domain and to inhibit the recognition of cargo signals.
Ubiquitinated.

Similarity:
Belongs to the GGA protein family.
Contains 1 GAE domain.
Contains 1 GAT domain.
Contains 1 VHS domain.

Database links:
UniProtKB/Swiss-Prot: Q9NZ52.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.xucheq.com 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
T66Y最新地址一地址二地址三| 韩国伦理电影网站| 久久国产成人午夜AV影院| 欧美大肥婆大肥BBBBB| 国产精品美女久久久免费| 国产精品美女WWW爽爽爽视频| 久久亚洲AV午夜福利精品一区 | 亚洲av无码一区二区二三区| 国产SM主人调教女M视频| 全免费A级毛片免费看| 亚洲国产精久久久久久久| 国产激情一区二区三区| AV动漫| 国产亚洲精品久久久久久| 国产手机精品一区二区| 日产一区二区| 国产欧美日韩A片免费软件| 国产精品扒开腿做爽爽爽视频| 午夜亚洲AV永久无码精品| 久久久久久久人妻无码中文字幕爆| 亚洲尺码与欧洲尺码区别入口跳转| 亚洲AV无码乱码在线观看性色| 国产成人无码A区在线观看视频| 凹凸国产熟女精品视频APP| 国产又色又爽无遮挡免费| 久久夜色精品国产噜噜亚洲AV| 亚洲AV永久无码精品一百度影院| 日木AV无码专区亚洲AV毛片| 亚洲AV色香蕉一区二区三区| 我把五十老女人弄高潮了| 日韩内射美女人妻一区二区三区| 老司机午夜福利视频| 再深点灬舒服灬受不了了视频| 亚洲HAIRY多毛PICS大全| 成年免费a级毛片免费看无码| 国产免费又色又爽粗视频| 久久精品99国产精品日本| 国产肉体XXXX裸体137大胆| 久久国产一区二区三区| 久久久亚洲精华液精华液精华液 | 最近中文字幕完整版免费高清 |