| 產(chǎn)品編號 | bs-10383R-BF488 |
| 英文名稱1 | Rabbit Anti-FGFR substrate 3/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的纖維母細(xì)胞生長因子受體底物3抗體 |
| 別 名 | FGFR signalling adaptor SNT2; FGFR substrate 3; Fibroblast growth factor receptor substrate 3; FRS2 beta; FRS2B; FRS3; FRS3 protein; MGC17167; SNT 2; Suc1 associated neurotrophic factor target 2 (FGFR signalling adaptor); Suc1 associated neurotrophic factor target 2; FRS3_HUMAN; FGFR-signaling adaptor SNT2; Suc1-associated neurotrophic factor target 2; SNT-2. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 信號轉(zhuǎn)導(dǎo) 生長因子和激素 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 54kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FGFR substrate 3 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. [provided by RefSeq, Jul 2008]. Function: Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2. Subunit: Binds NTRK1. Binds FGFR1, NGFR, GRB2, PTPN11 and ERK2. Subcellular Location: Membrane; Lipid-anchor. Tissue Specificity: Phosphorylated by ULK2 in vitro. Phosphorylated on tyrosine residues upon stimulation by BFGF or NGFB. Similarity: Contains 1 IRS-type PTB domain. Database links: Entrez Gene: 10817 Human Entrez Gene: 107971 Mouse Omim: 607744 Human SwissProt: O43559 Human SwissProt: Q91WJ0 Mouse Unigene: 194208 Human Unigene: 34398 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
