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Rabbit Anti-ALDH3A1/Gold Conjugated antibody (bs-15496R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@xucheq.com
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-15496R-Gold
英文名稱1 Rabbit Anti-ALDH3A1/Gold Conjugated antibody
中文名稱 膠體金標記的乙醛脫氫酶家族3成員A1抗體
別    名 AHD 4; AHD C; Ahd4; AHDC; AL3A1_HUMAN; Aldehyde dehydrogenase 3; Aldehyde dehydrogenase 3 family member A1; Aldehyde dehydrogenase 3 family, member A1; Aldehyde dehydrogenase 3A1; Aldehyde dehydrogenase; Aldehyde dehydrogenase class 3; Aldehyde dehydrogenase dimeric NADP preferring; Aldehyde dehydrogenase family 3 member A1; Aldehyde dehydrogenase family 3 subfamily A1; Aldehyde dehydrogenase isozyme 3; Aldehyde dehydrogenase type III; Aldehyde dehydrogenase, dimeric NADP preferring; ALDH 3; ALDH 3A1; ALDH III; ALDH3 A1; ALDH3; ALDH3A 1; Aldh3a1; ALDHIII; dimeric NADP-preferring; MGC10406; Stomach aldehyde dehydrogenase; Tumor associated aldehyde dehydrogenase tumor ALDH.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  細胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Pig, Horse, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ALDH3A1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Sep 2008].

Function:
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.

Subunit:
Homodimer.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
High levels in stomach, esophagus and lung; low level in the liver and kidney.

Similarity:
Belongs to the aldehyde dehydrogenase family.

Database links:

Entrez Gene: 218 Human

Entrez Gene: 11670 Mouse

Entrez Gene: 25375 Rat

Omim: 100660 Human

SwissProt: P30838 Human

SwissProt: P47739 Mouse

SwissProt: P11883 Rat

Unigene: 531682 Human

Unigene: 4257 Mouse

Unigene: 105627 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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