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Rabbit Anti-Nesprin 3/PE-Cy7 Conjugated antibody (bs-19209R-PE-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19209R-PE-Cy7
英文名稱1 Rabbit Anti-Nesprin 3/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的突觸核膜蛋白3抗體
別    名 C14orf49; Chromosome 14 open reading frame 49; FLJ25605; MGC75267; Nesp3; Nesprin3; Nesprin-3; NET53; Nuclear Envelope Spectrin Repeat Protein 3; Spectrin Repeat Containing, Nuclear Envelope Family Member 3; SYNE3; SYNE3_HUMAN.   
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 心血管  細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  結(jié)合蛋白  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse, Rat, 
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 112kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nesprin 3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system.

Subcellular Location:
Nucleus outer membrane. Located at the rough reticulum endoplasmic (RER) in some cells.

Similarity:
Belongs to the nesprin family.
Contains 1 KASH domain.
Contains 2 spectrin repeats.

Database links:

Entrez Gene: 490843 Dog

Entrez Gene: 100053652 Horse

Entrez Gene: 161176 Human

Entrez Gene: 212073 Mouse

Entrez Gene: 100525411 Pig

Entrez Gene: 299356 Rat

Omim: 610861 Human

SwissProt: Q6ZMZ3 Human

SwissProt: Q4FZC9 Mouse

Unigene: 354645 Human

Unigene: 212688 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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