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Rabbit Anti-EIF1AD/FITC Conjugated antibody (bs-14531R-FITC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-14531R-FITC
英文名稱1 Rabbit Anti-EIF1AD/FITC Conjugated antibody
中文名稱 FITC標(biāo)記的EIF1AD蛋白抗體
別    名 EIF1A_HUMAN; EIF1AD; Eukaryotic translation initiation factor 1A domain containing; Eukaryotic translation initiation factor 1A domain containing protein; Eukaryotic translation initiation factor 1A domain-containing protein; Haponin; Probable RNA binding protein EIF1AD; Probable RNA-binding protein EIF1AD.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)運(yùn)蛋白  新陳代謝  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Cynomolgus Monkey)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 19kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EIF1AD
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
eIF1AD is a 165 amino acid protein that belongs to the eIF1AD family and contains one S1-like domain. eIF1AD localizes to nucleus and is expressed in the glioblastoma cell line U-87 MG, the embryonic kidney cell line HEK-293, the pancreatic carcinoma cell line PANC-1, the breast carcinoma cell line MCF7, the lung cancer cell line NCI-H460, and the chronic myelogenous leukemia cell line K-562. eIF1AD interacts with GAPDH and may function to reduce cell proliferation. The gene encoding eIF1AD maps to human chromosome 11q13.1. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in chromosome 11.

Function:
Plays a role into cellular response to oxidative stress. Decreases cell proliferation.

Subunit:
Interacts with GAPDH and STAT1.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in the glioblastoma cell line U-87MG, the embryonic kidney cell line HEK-293, the pancreatic carcinoma cell line PANC-1, the breast carcinoma cell line MCF-7, the lung cancer cell line NCI-H460, and the chronic myelogenous leukemia cell line K-562.

Similarity:
Belongs to the EIF1AD family.
Contains 1 S1-like domain.

Database links:

Entrez Gene: 84285 Human

Entrez Gene: 615726 Cow

Entrez Gene: 69860 Mouse

Entrez Gene: 293673 Rat

SwissProt: Q58CY2 Cow

SwissProt: Q4R354 Cynomolgus Monkey

SwissProt: Q8N9N8 Human

SwissProt: Q3THJ3 Mouse

SwissProt: Q5RKI6 Rat

Unigene: 425178 Human

Unigene: 299167 Mouse

Unigene: 4163 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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