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Rabbit Anti-ELP4/PE-Cy3 Conjugated antibody (bs-14574R-PE-Cy3)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-14574R-PE-Cy3
英文名稱1 Rabbit Anti-ELP4/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的ELP4蛋白抗體
別    名 C11orf19; dJ68P15A.1; elongation protein 4 homolog (S. cerevisiae); Elongation protein 4 homolog; Elongator complex protein 4; ELP4; ELP4_HUMAN; FLJ20498; hELP4; PAX6 neighbor gene protein; PAX6NEB; PAXNEB.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ELP4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration. [provided by RefSeq, Jul 2008]

Function:
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Widely expressed

Similarity:
Belongs to the ELP4 family.

Database links:

Entrez Gene: 26610 Human

Entrez Gene: 77766 Mouse

Entrez Gene: 100514702 Pig

Entrez Gene: 691133 Rat

Entrez Gene: 550331 Zebrafish

Omim: 606985 Human

SwissProt: Q2TBH6 Cow

SwissProt: Q96EB1 Human

SwissProt: Q9ER73 Mouse

SwissProt: Q566Y1 Zebrafish

Unigene: 175534 Human

Unigene: 33870 Mouse

Unigene: 79765 Zebrafish



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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