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Rabbit Anti-EPS8L1/BF350 Conjugated antibody (bs-14616R-BF350)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-14616R-BF350
英文名稱1 Rabbit Anti-EPS8L1/BF350 Conjugated antibody
中文名稱 BF350標(biāo)記的EPS8L1蛋白抗體
別    名 DRC 3; DRC3; Epidermal growth factor receptor kinase substrate 8 like protein 1; Epidermal growth factor receptor kinase substrate 8-like protein 1; Epidermal growth factor receptor pathway substrate 8 related protein 1; Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8 like 1; EPS8 like protein 1; EPS8-like protein 1; EPS8-related protein 1; EPS8L 1; EPS8L 1; Eps8l1; EPS8R1; ES8L1; ES8L1_HUMAN; FLJ20258; MGC23164; MGC4642; PP10566; PP10566.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  生長因子和激素  細(xì)胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Sheep, Guinea Pig, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 80kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EPS8L1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.

Subunit:
Interacts with ABI1. Part of a complex that contains SOS1, ABI1 and EPS8L2. Associates with F-actin.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in placenta.

Similarity:
Belongs to the EPS8 family.
Contains 1 SH3 domain.

Database links:

Entrez Gene: 54869 Human

Entrez Gene: 67425 Mouse

Entrez Gene: 361503 Rat

Omim: 614987 Human

SwissProt: Q8TE68 Human

SwissProt: Q8R5F8 Mouse

Unigene: 438862 Human

Unigene: 360392 Mouse

Unigene: 138370 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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