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Rabbit Anti-NRIP2/BF488 Conjugated antibody (bs-19349R-BF488)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-19349R-BF488
英文名稱1 Rabbit Anti-NRIP2/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的核受體相互作用蛋白2抗體
別    名 DKFZp761G1913;; Neuronal interacting factor X 1; Nix1; Nrip2; NRIP2_HUMAN; Nuclear receptor interacting protein 2; Nuclear receptor-interacting protein 2.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  染色質(zhì)和核信號(hào)  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NRIP2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
NRIP2 is a 281 amino acid nuclear protein that down-regulates transcriptional activation by nuclear receptors such as ROR∫. The gene encoding NRIP2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.

Function:
Down-regulates transcriptional activation by nuclear receptors such as NR1F2.

Subunit:
Interacts with NR1F2, RARA and THRB in a ligand-dependent manner.

Subcellular Location:
Nucleus.

Database links:

Entrez Gene: 83714 Human

Entrez Gene: 60345 Mouse

SwissProt: Q9BQI9 Human

SwissProt: Q9JHR9 Mouse

Unigene: 530816 Human

Unigene: 269883 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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