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国产精品 高清 尿 小便 嘘嘘,大学生第一次破苞疼哭了
Rabbit Anti-Fascin 2/PE-Cy3 Conjugated antibody (bs-16028R-PE-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@xucheq.com
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@xucheq.com
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16028R-PE-Cy3
英文名稱1 Rabbit Anti-Fascin 2/PE-Cy3 Conjugated antibody
中文名稱 PE-Cy3標(biāo)記的Fascin 2蛋白抗體
別    名 Fascin homolog 2, actin bundling protein, retinal Strongylocentrotus purpuratus; Fascin Strongylocentrotus purpuratus homolog 2 actin bundling protein, retinal; Fascin-2; FSCN2; FSCN2_HUMAN; Retinal fascin; RFSN; RP30.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞骨架  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 55kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Fascin 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.

Subcellular Location:
Cytoplasm > cytoskeleton. Cell projection > stereocilium.

Tissue Specificity:
Localized specifically in the outer and inner segments of the photoreceptor cells in the retina.

DISEASE:
Defects in FSCN2 are the cause of retinitis pigmentosa type 30 (RP30) [MIM:607921]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP30 inheritance is autosomal dominant.

Similarity:
Belongs to the fascin family.

Database links:

Entrez Gene: 25794 Human

Entrez Gene: 337926 Cow

Entrez Gene: 483362 Dog

Entrez Gene: 238021 Mouse

Entrez Gene: 303741 Rat

Omim: 607643 Human

SwissProt: O18728 Cow

SwissProt: O14926 Human

SwissProt: Q32M02 Mouse

Unigene: 118555 Human

Unigene: 375010 Mouse

Unigene: 481403 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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