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Rabbit Anti-DPH4/BF594 Conjugated antibody (bs-14417R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-14417R-BF594
英文名稱1 Rabbit Anti-DPH4/BF594 Conjugated antibody
中文名稱 BF594標(biāo)記的DPH4蛋白抗體
別    名 1700030A21Rik; 2610027M02Rik; AV066965; AW240712; CSL type zinc finger containing protein 3; CSL-type zinc finger-containing protein 3; DJC24_HUMAN; DnaJ (Hsp40) homolog, subfamily C, member 24; DnaJ homolog subfamily C member 24; DNAJC24; DPH4 homolog (JJJ3, S. cerevisiae); DPH4 homolog; DPH4, JJJ3 homolog; JJJ3; MmDjC7; RGD1564710; RP23-232D1.6; ZCSL3; Zinc finger, CSL domain containing 3; Zinc finger, CSL type containing 3.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DPH4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]

Function:
Stimulates the ATPase activity of several Hsp70-type chaperones.

Subunit:
Monomer and homooligomer. Iron binding promotes oligomerization.

Subcellular Location:
Cytoplasm, cytoskeleton (By similarity).

Similarity:
Belongs to the DPH4 family.
Contains 1 DPH-type zinc finger.
Contains 1 J domain.

Database links:

Entrez Gene: 120526 Human

Entrez Gene: 99349 Mouse

Entrez Gene: 362184 Rat

Omim: 611072 Human

SwissProt: Q6P3W2 Human

SwissProt: Q91ZF0 Mouse

Unigene: 187269 Human

Unigene: 741895 Human

Unigene: 25661 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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