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Rabbit Anti-TRAPPC6A/APC Conjugated antibody (bs-16587R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-16587R-APC
英文名稱1 Rabbit Anti-TRAPPC6A/APC Conjugated antibody
中文名稱 APC標(biāo)記的TRAPPC6A蛋白抗體
別    名 1810073E21Rik; 4930519D19Rik; AI480686; HSPC289; MGC117907; mhyp; OTTMUSP00000025165; OTTMUSP00000025166; rCG_54352; RGD1309160; TPC6A_HUMAN; Trafficking protein particle complex 6A; Trafficking protein particle complex subunit 6A; TRAPP complex subunit 6A; TRAPPC6A; TRS33.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)運(yùn)蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Dog, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRAPPC6A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
TRAPPC6A is a 159 amino acid protein that localizes to the Golgi apparatus and endoplasmic reticulum. Belonging to the TRAPP small subunits family and the BET3 subfamily, TRAPPC6A may play a role in vesicular transport during the biogenesis of melanosomes. TRAPPC6A is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor. TRAPPC6A exists as a heterodimer with TRAPPC3 and undergoes alternative splicing to produce two isoforms. TRAPPC6A is encoded by a gene located on human chromosome 19, which consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a variety of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

Function:
May play a role in vesicular transport during the biogenesis of melanosomes.

Subunit:
Part of the multisubunit TRAPP (transport protein particle) complex. Heterodimer with TRAPPC3. The heterodimer TRAPPC3-TRAPPC6A interacts with TRAPPC2L. Interacts with TRAPPC2L.

Subcellular Location:
Golgi apparatus; cis-Golgi network. Endoplasmic reticulum.

Similarity:
Belongs to the TRAPP small subunits family. BET3 subfamily.

Database links:

Entrez Gene: 79090 Human

Omim: 610396 Human

SwissProt: O75865 Human

Unigene: 466929 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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