產(chǎn)品編號 | bs-16201R-Gold |
英文名稱1 | Rabbit Anti-FXL19/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的FXL19蛋白抗體 |
別 名 | F-box and leucine-rich repeat protein 19; F-box/LRR-repeat protein 19; FBL19; Fbxl19; FXL19_HUMAN; JHDM1C; Jumonji C domain containing histone demethylase 1C. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 細(xì)胞生物 跨膜蛋白 泛素 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 76kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FXL19 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This gene encodes a member of the Skp1-Cullin-F-box family of E3 ubiquitin ligases. The encoded protein is reported to bind to the transmembrane receptor interleukin 1 receptor-like 1 and regulate its ubiquitination and degradation. This protein has been linked to the regulation of pulmonary inflammation and psoriasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Subunit: Directly interacts with SKP1 and CUL1 (By similarity). Similarity: Contains 1 CXXC-type zinc finger. Contains 1 F-box domain. Contains 6 LRR (leucine-rich) repeats. Contains 1 PHD-type zinc finger. Database links: Entrez Gene: 54620 Human Entrez Gene: 233902 Mouse GenBank: BC059173 Human Omim: 609085 Human SwissProt: Q6PCT2 Human SwissProt: Q6PB97 Mouse Unigene: 152149 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |