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Rabbit Anti-GPHB5/AP Conjugated antibody (bs-16275R-AP)
訂購(gòu)熱線:400-901-9800
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-16275R-AP
英文名稱1 Rabbit Anti-GPHB5/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的糖蛋白激素β亞基5抗體
別    名 CGH; Glycoprotein hormone beta 5; GPHB5_HUMAN; Glycoprotein hormone beta 5 precursor; Glycoprotein hormone beta subunit; GPB5; Thyrostimulin subunit beta; ZLUT1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Sheep, Gorilla, Xenopus tropicalis , Elephant)
產(chǎn)品應(yīng)用 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 12kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPHB5
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
GPHB5 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).[supplied by OMIM, Mar 2008]

Function:
GPHB5 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family. Corticotroph-derived glycoprotein hormone (CGH), also referred to as thyrostimulin, is a noncovalent heterodimer of glycoprotein hormone alpha 2 (GPHA2) and glycoprotein hormone beta 5 (GPHB5).

Subunit:
Heterodimer with GPHA2.

Subcellular Location:
Secreted

Tissue Specificity:
Highly expressed in brain and at low levels in pituitary. Also found in retina, testis and skin but not in pancreas, parotid, kidney, stomach, liver, colon, small intestine, thyroid, brain or adrenal gland. In pituitary, colocalizes with ACTH, suggesting that it is located in corticotrophs.

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the glycoprotein hormones subunit beta family.

Database links:

Entrez Gene: 122876 Human

Entrez Gene: 217674 Mouse

Omim: 609652 Human

SwissProt: Q86YW7 Human

SwissProt: Q812B2 Mouse

Unigene: 375028 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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