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Rabbit Anti-TOM1/BF488 Conjugated antibody (bs-17222R-BF488)
訂購熱線:400-901-9800
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訂購QQ:  400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17222R-BF488
英文名稱1 Rabbit Anti-TOM1/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的TOM1蛋白抗體
別    名 FLJ33404; OTTHUMP00000028777; Target of myb 1; TOM1_HUMAN; Target of Myb protein 1; Target of myb1; TOM 1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  轉(zhuǎn)運蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Chimpanzee, Rhesus monkey)
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 54kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TOM1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Function:
TOM1 may be involved in intracellular trafficking. In conjunction with Tollip it plays an important role in recruiting clathrin onto endosomes and may modulate endosomal functions.

Subunit:
Interacts with ZFYVE16; interaction is required to target it to endosomes.

Subcellular Location:
Cytoplasm. Membrane; Peripheral membrane protein

Tissue Specificity:
Widely expressed. Highly expressed in skeletal muscle, heart, placenta and liver

Similarity:
Belongs to the TOM1 family.
Contains 1 GAT domain.
Contains 1 VHS domain.

Database links:

Entrez Gene: 10043 Human

Entrez Gene: 608746 Dog

Entrez Gene: 21968 Mouse

Entrez Gene: 361370 Rat

Entrez Gene: 717499 Rhesus monkey

Omim: 604700 Human

SwissProt: O60784 Human

SwissProt: O88746 Mouse

SwissProt: Q5XI21 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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